{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T21:32:13Z","timestamp":1790026333702,"version":"4.0.1"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T00:00:00Z","timestamp":1625011200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Photodynamic therapy for hidradenitis suppurativa (HS) is a therapeutic alternative with a good safety profile, but its effectiveness has yet to be demonstrated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To demonstrate the effectiveness of PDT with intralesional methylene blue in HS lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cross\u2010sectional study was performed. Forty\u2010one patients were treated with intralesional methylene blue and a diode lamp. Follow\u2010up was carried out at 1 and 6\u00a0months after therapy. Efficacy was determined by the diameter reduction of the lesion measured by high\u2010frequency ultrasound.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A reduction of \u226575% in the maximum diameter was recorded in 58.5% of the lesions, while 22% showed a reduction between 50% and 75%, and 19.5% showed a reduction of &lt;50%. Recurrence rate was 12.5%. The lesions treated in patients with typical forms of HS (Canoui\u2010Poitrine phenotype I) had a better therapeutic response. No statistically significant differences were found in terms of lesion location or concomitant treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This therapy may potentially be a cost\u2010effective and well\u2010tolerated local therapy for Hurley I\u2010II patients with superficial abscesses and fistulas.<\/jats:p><\/jats:sec>","DOI":"10.1111\/phpp.12709","type":"journal-article","created":{"date-parts":[[2021,6,22]],"date-time":"2021-06-22T18:47:26Z","timestamp":1624387646000},"page":"12-18","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Ultrasound\u2010guided photodynamic therapy with intralesional methylene blue and a 635 nm light\u2010emitting diode lamp in hidradenitis suppurativa: A retrospective study of 41 patients"],"prefix":"10.1111","volume":"38","author":[{"given":"Marta","family":"Gamissans","sequence":"first","affiliation":[{"name":"Department of Dermatology Hospital Parc Taul\u00ed  Sabadel Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N\u00faria","family":"Riera\u2010Mart\u00ed","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Parc Taul\u00ed  Sabadel Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Roman\u00ed","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Parc Taul\u00ed  Sabadel Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yolanda","family":"Gilaberte","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Miguel Servet  Zaragoza Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,6,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12966"},{"key":"e_1_2_8_3_1","first-page":"500","article-title":"Antimicrobial photodynamic therapy: an unexplored 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