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Several therapeutic options have been employed in vitiligo including topical and oral drugs, surgical techniques, and phototherapy which is considered the cornerstone treatment. Different wavelengths and modalities are available, but narrowband UVB (NB\u2010UVB) is considered the safest and the most effective phototherapy alternative. NB\u2010UVB acts on multiple steps in vitiligo pathogenesis, and it is capable of inducing stabilization and repigmentation of vitiligo lesions. Technological advances have led to the development of both new phototherapy devices and new medical and surgical therapeutic options that can be combined with phototherapy to achieve optimal results. There is no standard treatment, and individual patient and disease characteristics should be considered. We review the current evidence in what concerns UVB phototherapy for vitiligo treatment, including novel combination treatments that may help to provide the best care for these patients.<\/jats:p>","DOI":"10.1111\/phpp.12740","type":"journal-article","created":{"date-parts":[[2021,10,9]],"date-time":"2021-10-09T16:00:39Z","timestamp":1633795239000},"page":"215-223","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["UVB phototherapy in the treatment of vitiligo: State of the art and clinical perspectives"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5034-3613","authenticated-orcid":false,"given":"Rita","family":"Bouceiro Mendes","sequence":"first","affiliation":[{"name":"Dermatology Department Centro Hospitalar e Universit\u00e1rio Lisboa Norte  Lisbon 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