{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T23:13:05Z","timestamp":1780614785578,"version":"3.54.1"},"reference-count":29,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T00:00:00Z","timestamp":1637712000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Artificial white LED light photodynamic therapy (awl\u2010PDT) is an effective, pain\u2010free treatment for actinic keratosis. The efficacy of awl\u2010PDT in the treatment of superficial basal cell carcinoma (sBCC) has not been assessed. Patients with histologically confirmed sBCC underwent two treatments of awl\u2010PDT 1\u00a0week apart. Lesions were incubated with methyl 5\u2010aminolaevulinic acid for 30\u00a0min and then illuminated using the Maquet Power LED 500 theatre light (405\u2010800nm, 140\u00a0000 lux) to deliver an equivalent red light dose of 75\u00a0J\/cm<jats:sup>2<\/jats:sup> at a rate of 55\u00a0mW\/cm<jats:sup>2<\/jats:sup>. Pain was measured using a visual analogue scale during treatment. Clinical response was assessed at day 28. Follow\u2010up continued 3\u00a0months for 1\u00a0year. Cosmetic outcome was assessed at 3\u00a0months and 1\u00a0year. Twenty\u2010eight patients with 36 lesions and a mean age of 63.64 (SD 2.62) were recruited. The median lesion size was 15\u00a0mm (IQR 8.75). The response rate at day 28 was 100%. Recurrence rates were 3\/36 (8.3%) at 3\u00a0months, 6\/36 (16.7%) at 6\u00a0months, 10\/36 (27.8%) at 9\u00a0months and 11\/36 (30.6%) at 1\u00a0year. Median pain scores were 0\/100 (IQR 0) and 0\/100 (IQR 5) during treatments one and two, respectively. Cosmetic outcome was excellent or good in the majority of cases. Although initially effective for sBCC at 28\u00a0days, 30.6% of lesions recurred 1\u00a0year after awl\u2010PDT. Pain scores were negligible, and the cosmetic outcome was favourable. Further head\u2010to\u2010head studies with optimised protocols are required to determine if awl\u2010PDT has a role in the treatment of sBCC.<\/jats:p>","DOI":"10.1111\/phpp.12750","type":"journal-article","created":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T18:03:49Z","timestamp":1635962629000},"page":"322-327","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["An open\u2010label prospective study to assess short incubation time white LED light photodynamic therapy in the treatment of superficial basal cell carcinoma"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7290-7283","authenticated-orcid":false,"given":"Rebecca","family":"Hellen","sequence":"first","affiliation":[{"name":"Department of Dermatology The Charles Centre, St. Vincent's University Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eilis 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