{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T19:11:26Z","timestamp":1776193886701,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,1,31]],"date-time":"2022-01-31T00:00:00Z","timestamp":1643587200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82073445"],"award-info":[{"award-number":["82073445"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81903247"],"award-info":[{"award-number":["81903247"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20190145"],"award-info":[{"award-number":["BK20190145"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20210049"],"award-info":[{"award-number":["BK20210049"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>A light emitting diode (LED), with a wavelength of 308\u00a0nm, has been utilized in the dermatologic treatment of vitiligo.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We investigated the efficacy and safety of 308\u2010nm LED for use in the treatment of vitiligo.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective study of 70 stable\u2010stage vitiligo patients (with a total of 99 lesions) who received 308\u2010nm LED treatment at the Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College from June 2018 to June 2020. Treatment efficacy was evaluated after 8 treatment sessions, 16 treatment sessions, and the final treatment session, to estimate the percentage of re\u2010pigmentation in the treated area. The Kruskal\u2013Wallis test was used for data analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Based on the final treatment session analysis of all 99 lesions, 0 lesions showed no response, 21 lesions showed poor response, 29 lesions showed moderate response, 23 lesions showed good response, and 26 lesions showed excellent response. The efficacy rate was 49.49%, and there was a significant correlation between the six distinct anatomical regions treated and re\u2010pigmentation grade (\u03c7<jats:sup>2<\/jats:sup>\u00a0=\u00a013.419, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.009). Among these regions, facial lesions showed the best response to treatment, while the hands and feet lesions showed the poorest response.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The clinical efficacy of 308\u2010nm LED treatment is limited based on the treatment area. It demonstrated significant practical application in the treatment of vitiligo.<\/jats:p><\/jats:sec>","DOI":"10.1111\/phpp.12777","type":"journal-article","created":{"date-parts":[[2022,1,25]],"date-time":"2022-01-25T01:47:59Z","timestamp":1643075279000},"page":"489-494","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Treatment of vitiligo with 308\u2010nm light emitting diode: Our experience from a two\u2010year follow\u2010up of Chinese patients"],"prefix":"10.1111","volume":"38","author":[{"given":"Chao","family":"Luan","sequence":"first","affiliation":[{"name":"Institute of Dermatology Chinese Academy of Medical Sciences and Peking Union Medical College  Nanjing Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Hu","sequence":"additional","affiliation":[{"name":"Institute of Dermatology Chinese Academy of Medical Sciences and Peking Union Medical College  Nanjing Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Ju","sequence":"additional","affiliation":[{"name":"Institute of Dermatology Chinese Academy of Medical Sciences and Peking Union Medical College  Nanjing Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Huang","sequence":"additional","affiliation":[{"name":"Institute of Dermatology Chinese Academy of Medical Sciences and Peking Union Medical College  Nanjing Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong\u2010Lin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Dermatology Chinese Academy of Medical Sciences and Peking Union Medical College  Nanjing Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao\u2010Hua","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Dermatology Chinese Academy of Medical Sciences and Peking Union Medical College  Nanjing Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pan\u2010Pan","family":"Tian","sequence":"additional","affiliation":[{"name":"Institute of Dermatology Chinese Academy of Medical Sciences and Peking Union Medical College  Nanjing Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Zhu","sequence":"additional","affiliation":[{"name":"Institute of Dermatology Chinese Academy of Medical Sciences and Peking Union Medical College  Nanjing Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Zhuang","sequence":"additional","affiliation":[{"name":"Institute of Dermatology Chinese Academy of Medical Sciences and Peking Union Medical College  Nanjing Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia\u2010An","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Dermatology Chinese Academy of Medical Sciences and Peking Union Medical College  Nanjing Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kun","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Dermatology Chinese Academy of Medical Sciences and Peking Union Medical College  Nanjing Jiangsu 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