{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:56:04Z","timestamp":1747187764198,"version":"3.40.5"},"reference-count":12,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,9,14]],"date-time":"2022-09-14T00:00:00Z","timestamp":1663113600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 41\u2010year\u2010old man with oral <jats:italic>pemphigus vulgaris<\/jats:italic> (PV) presented to our clinic with a history of no response to numerous immunosuppressant agents and was referred for extracorporeal photopheresis (ECP) therapy. Although the patient underwent a high\u2010intensity ECP regimen for 5\u00a0months, which included two different photopheresis systems, his oral dysesthesia continued to interfere with oral intake, leading to continued weight loss and other adverse events. The intervention was associated with changes in several immune cell subpopulations without modifying the anti\u2010epidermal antibody titers, aligned with his poor clinical outcome. To the best of the authors' knowledge, this is the first report to examine immunophenotyping of a PV patient who was refractory to previous immunosuppression and recalcitrant to high\u2010intensity ECP therapy.<\/jats:p>","DOI":"10.1111\/phpp.12834","type":"journal-article","created":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T09:18:20Z","timestamp":1662110300000},"page":"296-300","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Refractory pemphigus vulgaris and high\u2010intensity extracorporeal photopheresis: A case report"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8169-9914","authenticated-orcid":false,"given":"Yandy Marx","family":"Castillo\u2010Aleman","sequence":"first","affiliation":[{"name":"Abu Dhabi Stem Cells Center (ADSCC)  Abu Dhabi United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6209-0393","authenticated-orcid":false,"given":"Antonio Alfonso","family":"Bencomo\u2010Hernandez","sequence":"additional","affiliation":[{"name":"Abu Dhabi Stem Cells Center (ADSCC)  Abu Dhabi United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5373-3414","authenticated-orcid":false,"given":"Yendry","family":"Ventura\u2010Carmenate","sequence":"additional","affiliation":[{"name":"Abu Dhabi Stem Cells Center (ADSCC)  Abu Dhabi United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7478-0482","authenticated-orcid":false,"given":"Carlos Agustin","family":"Villegas\u2010Valverde","sequence":"additional","affiliation":[{"name":"Abu Dhabi Stem Cells Center (ADSCC)  Abu Dhabi United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7222-727X","authenticated-orcid":false,"given":"Rene Antonio","family":"Rivero\u2010Jimenez","sequence":"additional","affiliation":[{"name":"Abu Dhabi Stem Cells Center (ADSCC)  Abu Dhabi United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"ADSCC ECP Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,9,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)31778-7"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21705"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15930"},{"issue":"6","key":"e_1_2_10_5_1","first-page":"647","article-title":"Treatment of autoimmune disease with extracorporeal photochemotherapy: pemphigus vulgaris \u2013 preliminary report","volume":"62","author":"Rook AH","year":"1989","journal-title":"Yale J Biol Med"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0190-9622(08)80560-9"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/ajts.AJTS_87_16"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2020.11.008"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-020-0760-z"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10875-021-00991-y"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/cei.13232"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0134518"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-022-01189-z"}],"container-title":["Photodermatology, Photoimmunology &amp; 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