{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T02:41:34Z","timestamp":1785552094417,"version":"3.56.0"},"reference-count":13,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T00:00:00Z","timestamp":1670371200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Vitiligo is a cosmetically concerning common disorder of depigmentation. Narrowband Ultraviolet B (NB\u2010UVB) phototherapy is a well\u2010established mode of treatment for vitiligo. Microneedling is a simple method that has been used for vitiligo treatment in adjunct with NB\u2010UVB and has been shown to induce repigmentation in a few studies; however, there is limited study in the literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To compare the efficacy of NB\u2010UVB alone versus NB\u2010UVB in conjunction with microneedling in patients of stable vitiligo.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty patients of non\u2010segmental vitiligo with patches tending toward symmetry, stable for at least 6\u2009months were included. Patches on right side of body (side A) were subjected to both microneedling every 2\u2009weeks and NB\u2010UVB three times a week, while patches on left side of body (side B) were subjected to NB\u2010UVB alone thrice weekly for 4\u2009months or till complete resolution of lesions whichever was earlier. Patients were followed up for another 2\u2009months. Response was assessed by photographic record and Vitiligo Area Severity Index (VASI score) calculated at baseline and every month for 6\u2009months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean VASI score improvement in both the groups as compared to baseline was statistically significant (<jats:italic>p<\/jats:italic>\u2010value\u2009&lt;\u2009.01). However, the difference in mean VASI scores between the two groups was not statistically significant (<jats:italic>p<\/jats:italic>\u2010value\u00a0=\u00a0.17).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>NB\u2010UVB is an effective modality for treatment of vitiligo, but there is no additional benefit of combining microneedling with it.<\/jats:p><\/jats:sec>","DOI":"10.1111\/phpp.12847","type":"journal-article","created":{"date-parts":[[2022,11,24]],"date-time":"2022-11-24T12:50:38Z","timestamp":1669294238000},"page":"357-363","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A comparative interventional study of narrowband ultraviolet B alone and narrowband ultraviolet B in combination with microneedling in patients with stable vitiligo"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2307-0971","authenticated-orcid":false,"given":"Aneet","family":"Kaur","sequence":"first","affiliation":[{"name":"Department of Dermatology Maulana Azad Medical College  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishna Deb","family":"Barman","sequence":"additional","affiliation":[{"name":"Department of Dermatology Maulana Azad Medical College  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bijaylaxmi","family":"Sahoo","sequence":"additional","affiliation":[{"name":"Department of Dermatology Maulana Azad Medical College  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priya","family":"Choudhary","sequence":"additional","affiliation":[{"name":"Department of Dermatology Maulana Azad Medical College  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(98)70194-X"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.10.043"},{"key":"e_1_2_9_4_1","first-page":"1","article-title":"Needle Sheikhing treatment of vitiligo, a study of needling + UVB for vitiligo","volume":"1","author":"Sheikh MI","year":"2017","journal-title":"Cosmetol J"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.5.578"},{"key":"e_1_2_9_6_1","first-page":"177","article-title":"Original Article Efficacy of narrowband ultraviolet B phototherapy with needling in patients of vitiligo","volume":"25","author":"Batool S","year":"2015","journal-title":"J Pak Assoc Dermatol."},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12061"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000000924"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.05.033"},{"key":"e_1_2_9_10_1","first-page":"2011","article-title":"A comparison between the efficacy of narrow band ultra violet B phototherapy with and without needling of the lesion in the treatment of vitiligo","volume":"17","author":"Mohaghegh F","year":"2012","journal-title":"J Res Med Sci."},{"key":"e_1_2_9_11_1","first-page":"149","article-title":"Needling: An adjunct to narrowband ultraviolet B therapy in localized fixed vitiligo","volume":"18","author":"Ahmad TJ","year":"2008","journal-title":"J Pak Assoc Dermatol."},{"key":"e_1_2_9_12_1","first-page":"89","article-title":"Efficacy and tolerability of needling as an adjuvant to narrowband ultraviolet B therapy in the treatment of vitiligo: A clinical trial","volume":"16","author":"Ebadi A","year":"2013","journal-title":"Iran J Dermatol."},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/2013.jamadermatol.386"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12072"}],"container-title":["Photodermatology, Photoimmunology &amp; Photomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/phpp.12847","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/phpp.12847","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/phpp.12847","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T07:53:40Z","timestamp":1692345220000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/phpp.12847"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,7]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["10.1111\/phpp.12847"],"URL":"https:\/\/doi.org\/10.1111\/phpp.12847","archive":["Portico"],"relation":{},"ISSN":["0905-4383","1600-0781"],"issn-type":[{"value":"0905-4383","type":"print"},{"value":"1600-0781","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,7]]},"assertion":[{"value":"2022-04-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}