{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T22:16:36Z","timestamp":1757542596330,"version":"3.40.5"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T00:00:00Z","timestamp":1672099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32060177"],"award-info":[{"award-number":["32060177"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81860553"],"award-info":[{"award-number":["81860553"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>HIV\/AIDS patients are susceptible to various infectious and inflammatory dermatoses. No systemic work has been done on HIV\/AIDS patients with immune\u2010mediated photodermatoses in China. Here, we aim to determine the clinical features of immune\u2010mediated photodermatoses in HIV\/AIDS patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis of HIV\/AIDS patients with immune\u2010mediated photodermatoses was carried out with demographic data, clinical characteristics, laboratory data, and follow\u2010up data at the First Affiliated Hospital of Kunming Medical University between 2012 and 2019. The data were subjected to statistical analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 39 HIV\/AIDS patients with immune\u2010mediated photodermatoses were enrolled, including 22 cases of polymorphic light eruption (PLE), 16 cases of chronic actinic dermatitis (CAD), and one actinic reticuloid. The CD4 count at the visit of the HIV\u2010positive CAD group was lower than the PLE group (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.049). The HIV\u2010positive CAD group was more sensitive toward UVB than the PLE group (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.020) and had a lower MED\u2010UVB value (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.044). There was no significant difference in UV tests among different categories of skin types.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Immune\u2010mediated photodermatoses are a manifestation of the advanced symptom of HIV infection, and sometimes also the presenting feature of HIV infection. Compared with HIV\u2010positive PLE patients, CAD patients showed higher sensitivity to UVB radiation and had a lower MED\u2010UVB value. The primary treatment for immune\u2010mediated photodermatoses in HIV\/AIDS patients is HAART and sun avoidance.<\/jats:p><\/jats:sec>","DOI":"10.1111\/phpp.12853","type":"journal-article","created":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T13:08:51Z","timestamp":1671541731000},"page":"140-146","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical characteristics of patients with human immunodeficiency virus and immune\u2010mediated photodermatoses: A retrospective study of 39 patients"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4414-0219","authenticated-orcid":false,"given":"Lu\u2010Hui","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology First Affiliated Hospital of Kunming Medical University  Kunming China"},{"name":"NHC Key Laboratory of Drug Addiction Medicine, First Affiliated Hospital of Kunming Medical 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