{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T01:25:36Z","timestamp":1787793936529,"version":"build-2784847793"},"reference-count":42,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T00:00:00Z","timestamp":1679875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Mycosis fungoides (MF) and Sezary Syndrome are the most common forms of cutaneous T\u2010cell lymphoma. Early\u2010stage MF is known to have an indolent behavior, and the EORTC guidelines recommend treating patients with skin\u2010directed therapies, such as phototherapy, instead of systemic therapies. Phototherapy is a popular therapeutic option, with two commonly used light sources\u2014PUVA and narrow band\u2010nb UVB. PUVA is less commonly used due to its potential carcinogenic role, but it has systemic effects, while nb\u2010UVB has mostly skin\u2010limited effects. There is ongoing debate regarding the role of UVB light, and in 2021, the Cutaneous Lymphoma Italian Study Group reached a consensus on technical schedules for NB\u2010UVB and PUVA for MF. This study aims to analyze and compare the efficacy of the two phototherapy options in treating early\u2010MF patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>The study included patients diagnosed with stage IA\/B MF in the last 10\u2009years, who had at least 12\u2009months of follow\u2010up data and a minimum of 24 phototherapy sessions (PUVA or nb UVB) and treated with topical steroids apart from phototherapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Results showed that the two phototherapy options were similarly effective in treating early MF, with no significant differences in clinical response, although PUVA was associated with more adverse effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The study provides valuable insights into the use of phototherapy in early MF, and the results can be used to guide treatment decisions and improve patient outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/phpp.12873","type":"journal-article","created":{"date-parts":[[2023,3,28]],"date-time":"2023-03-28T05:21:32Z","timestamp":1679980892000},"page":"435-440","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["<scp>Nb\u2010UVB<\/scp> and <scp>PUVA<\/scp> therapy in treating early stages of Mycosis Fungoides: A single\u2010center cross\u2010sectional study"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3323-9216","authenticated-orcid":false,"given":"Corrado","family":"Zengarini","sequence":"first","affiliation":[{"name":"Dipartimento di Scienze Mediche e Chirurgiche Universit\u00e0 di Bologna  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregorio","family":"Baruffaldi","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Mediche e Chirurgiche Universit\u00e0 di Bologna  Bologna 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