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Phototherapy has emerged as a prominent treatment option for vitiligo, utilizing various light modalities to induce disease stability and repigmentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims and Methods<\/jats:title><jats:p>This narrative review aims to explore the clinical applications and molecular mechanisms of phototherapy in vitiligo.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results and Discussion<\/jats:title><jats:p>The review evaluates existing literature on phototherapy for vitiligo, analyzing studies on hospital\u2010based and home\u2010based phototherapy, as well as outcomes related to stabilization and repigmentation. Narrowband ultra\u2010violet B, that is, NBUVB remains the most commonly employed, studied and effective phototherapy modality for vitiligo. Special attention is given to assessing different types of lamps, dosimetry, published guidelines, and the utilization of targeted phototherapy modalities. Additionally, the integration of phototherapy with other treatment modalities, including its use as a depigmenting therapy in generalized\/universal vitiligo, is discussed. Screening for anti\u2010nuclear antibodies and tailoring approaches for non\u2010photo\u2010adapters are also examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In conclusion, this review provides a comprehensive overview of phototherapy for vitiligo treatment. It underscores the evolving landscape of phototherapy and offers insights into optimizing therapeutic outcomes and addressing the challenges ahead. By integrating clinical evidence with molecular understanding, phototherapy emerges as a valuable therapeutic option for managing vitiligo, with potential for further advancements in the field.<\/jats:p><\/jats:sec>","DOI":"10.1111\/phpp.12968","type":"journal-article","created":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T04:39:42Z","timestamp":1713415182000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Phototherapy for vitiligo: A narrative review on the clinical and molecular aspects, and recent literature"],"prefix":"10.1111","volume":"40","author":[{"given":"Anuradha","family":"Bishnoi","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology Postgraduate Institute of Medical Education and Research Chandigarh 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