{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T23:59:55Z","timestamp":1771459195814,"version":"3.50.1"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T00:00:00Z","timestamp":1742774400000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Vitiligo is a depigmenting autoimmune disease. This study aimed to determine the minimal erythema dose (MED) of vitiligo\u2010affected skin and normal skin among patients with skin phototype III, IV, and V.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study was performed. MED was determined using a handheld device with wavelength of 311\u2009nm. Vitiligo severity was measured using the Vitiligo Area Scoring Index (VASI) while disease activity was assessed by the Vitiligo Disease Activity (VIDA). Sun exposure was quantified by the Sun Exposure Index (SEI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 36 patients (mean age of 49.06\u2009\u00b1\u200921.29\u2009years old) participated with 12 patients from each skin phototype. MEDs of skin affected by vitiligo were 255\u2009\u00b1\u2009120.3, 280\u2009\u00b1\u200993.4, and 525\u2009\u00b1\u2009226.1\u2009mJ\/cm<jats:sup>2<\/jats:sup> for phototypes III, IV, and V respectively. The MEDs of unaffected skin were 465\u2009\u00b1\u2009120.3, 580\u2009\u00b1\u2009123.6, and 1150\u2009\u00b1\u2009116.8\u2009mJ\/cm<jats:sup>2<\/jats:sup> for phototypes III, IV, and V respectively. The MEDs for skin affected by vitiligo were 45%, 52%, and 54% less than the MEDs of unaffected skin for phototypes III, IV, and V respectively. The differences in MEDs between vitiligo\u2010affected skin and unaffected skin were significant for all skin phototypes (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). MED of skin with vitiligo negatively correlated with vitiligo severity, <jats:italic>r<\/jats:italic>\u2009=\u2009\u22120.426, <jats:italic>p<\/jats:italic>\u2009=\u20090.01. There were no significant correlations between MED and VIDA, disease duration, or SEI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>MED of skin with vitiligo was much lower than unaffected skin, and MEDs between skin phototypes III, IV, and V differed despite similar depigmentation. MED was not influenced by vitiligo disease activity, duration, or sun exposure.<\/jats:p><\/jats:sec>","DOI":"10.1111\/phpp.70015","type":"journal-article","created":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T23:40:33Z","timestamp":1742946033000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparison of Minimal Erythema Dose Between Affected and Unaffected Skin in Vitiligo Patients With Fitzpatrick Skin Phototypes <scp>III<\/scp>, <scp>IV<\/scp>, and V"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3340-5805","authenticated-orcid":false,"given":"Hui Wenn","family":"Chin","sequence":"first","affiliation":[{"name":"Department of Dermatology Hospital Raja Permaisuri Bainun  Ipoh Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adawiyah","family":"Jamil","sequence":"additional","affiliation":[{"name":"Department of Medicine Faculty of Medicine, University Kebangsaan Malaysia  Kuala Lumpur Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madiha","family":"Muhamad Sarkan","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Raja Permaisuri Bainun  Ipoh Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jyh Jong","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Raja Permaisuri Bainun  Ipoh Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,3,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000506103"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-2667(24)00026-4"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.20596"},{"issue":"3","key":"e_1_2_9_5_1","first-page":"365","article-title":"S1 Guideline: Diagnosis and Therapy of Vitiligo","volume":"20","author":"B\u00f6hm M.","year":"2022","journal-title":"Journal der Deutschen Dermatologischen Gesellschaft"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2017.0002"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/JD9.0000000000000151"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346\u20108138.12099"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13933"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.12.041"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.135.4.407"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.140.6.677"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/jim\u20102021\u2010002062"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8709.2012.00422.x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.4103\/ipj.ipj_74_23"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257\u2010021\u201000631\u20106"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000354607"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468\u20103083.2011.04131.x"},{"key":"e_1_2_9_19_1","first-page":"92","article-title":"A Clinical Study of Vitiligo","volume":"68","author":"Martis J.","year":"2002","journal-title":"Indian Journal of Dermatology, Venereology and Leprology"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16206"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1994.tb01250.x"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0929-6646(08)60071-6"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.1997.tb00223.x"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.1997.tb00233.x"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12410"},{"issue":"3","key":"e_1_2_9_26_1","first-page":"140","article-title":"Med Estimation for Narrow Band UV\u2010B on Type IV and Type V Skin in India","volume":"68","author":"Pai G. 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