{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:11:45Z","timestamp":1787242305273,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,8,10]],"date-time":"2025-08-10T00:00:00Z","timestamp":1754784000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["88887.859011\/2023\u201000"],"award-info":[{"award-number":["88887.859011\/2023\u201000"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["88887.798836\/2022\u201000"],"award-info":[{"award-number":["88887.798836\/2022\u201000"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background\/Purpose<\/jats:title>\n                    <jats:p>The therapeutic use of low\u2010level lasers aims to promote tissue photobiomodulation without raising the local temperature. However, in darker\u2010skin patients, melanin can increase temperature and cause adverse effects such as photosensitivity, especially in protocols with higher irradiances, such as those used in dual irradiations. Therefore, through a retrospective cohort, this project assesses the relationship between self\u2010reported skin color and the frequency of photosensitivity in patients treated with simultaneous dual irradiation protocols at the School of Dentistry of the University of S\u00e3o Paulo.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from patients treated with lasers between 2013 and 2023 were retrieved. Patients were divided into two groups based on skin color and assessed for photosensitivity after simultaneous irradiation with red and infrared wavelengths. Statistical analyses investigated the relationship between photosensitivity, skin color, patient characteristics, and delivered energy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Self\u2010reported skin color was associated with photosensitivity, with dark\u2010skinned patients having a three times higher risk of heating or thermal injury. The risk of clinically visible thermal injuries was nearly 12 times higher for this group compared to those with lighter skin. There was no correlation between the energy used and the degree of photosensitivity, nor was there a significant difference in energy between patients with and without photosensitivity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Self\u2010reported skin color was associated with photosensitivity occurrence during simultaneous laser wavelengths irradiation. Further studies are needed to investigate the mechanisms underlying the relation between melanin and irradiance. Finally, individualized photobiomodulation protocols are needed to ensure patient safety and optimize the therapy's expected effects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/phpp.70042","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T06:34:18Z","timestamp":1754894058000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Photosensitivity Episodes Related to Skin Color in People Treated With Dual\u2010Wavelength Low Power Laser Therapy: A Retrospective Cohort Study"],"prefix":"10.1111","volume":"41","author":[{"given":"Caio Bruno Tolentino","family":"de Brito","sequence":"first","affiliation":[{"name":"School of Dentistry University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6405-2270","authenticated-orcid":false,"given":"Caio 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