{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T23:47:33Z","timestamp":1792540053179,"version":"4.5.0"},"reference-count":72,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T00:00:00Z","timestamp":1756944000000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Narrowband\u2010ultraviolet B (NB\u2010UVB) phototherapy is an effective treatment for psoriasis in patients who have failed topical regimens or those who desire to avoid systemic treatment. Despite its regular use in non\u2010white individuals, NB\u2010UVB treatment response for psoriasis in skin of color (SOC) has not been systematically reviewed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a systematic review on the basis of the Preferred Reporting Items for Systematic Reviews and Meta\u2010Analyses (PRISMA) on all available studies to date assessing NB\u2010UVB for psoriasis treatment in skin of color (SOC) (up to 15 November 2024). The primary outcome was qualitative data on clinical outcomes of UVB (PASI 75). Random\u2010effects meta\u2010analysis was performed to assess treatment responses. Secondary outcomes of biochemical and immunologic mechanisms of NB\u2010UVB, NB\u2010UVB in combination with other treatments, and NB\u2010UVB compared to other forms of phototherapy were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 1283 articles initially identified, 54 were ultimately included for formal review. We identified 43 articles assessing clinical outcomes of NB\u2010UVB phototherapy in patients with Fitzpatrick skin type III\u2013IV for a total of 1322 patients with chronic plaque psoriasis and 12 patients with palmoplantar psoriasis. Nine studies were included for meta\u2010analysis of PASI75 response; 70.5% of patients achieved PASI75, and all studies demonstrated statistically significant PASI improvement after treatment. NB\u2010UVB demonstrated a higher rate of complete clearance when compared to BB\u2010UVB but did not result in a statistically significant difference in the proportion of the patient population achieving PASI75 when compared to PUVA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Phototherapy is effective for the treatment of psoriasis in SOC patients and remains a valuable treatment option despite the advent of various topical, systemic, and biologic treatments for psoriasis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/phpp.70051","type":"journal-article","created":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T03:45:01Z","timestamp":1757043901000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Narrowband\u2010Ultraviolet B Phototherapy for Psoriasis Treatment in Skin of Color: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-2598-293X","authenticated-orcid":false,"given":"Megan","family":"Hauptman","sequence":"first","affiliation":[{"name":"Department of Dermatology University of Miichigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amjad","family":"El Othmani","sequence":"additional","affiliation":[{"name":"School of Medicine Wayne State University  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svati","family":"Pazhyanur","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Miichigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1367-742X","authenticated-orcid":false,"given":"Mio","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Miichigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,4]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"National Psoriasis Foundation \u201cPsoriasis Statistics. Get the Facts About Psoriasis and Psoriatic Arthritis \u201daccessed December 9 2024."},{"key":"e_1_2_9_3_1","article-title":"National, Regional, and Worldwide Epidemiology of Psoriasis: Systematic Analysis and Modelling Study","volume":"369","author":"Parisi R.","year":"2020","journal-title":"BMJ (Clinical Research Ed.)"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.11.013"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-013-0015-y"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-11-15"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2010.01345.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12822"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2018.1543848"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-024-02880-x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2019.1670778"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2021.1967265"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2020.1757018"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.14606"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.14446"},{"key":"e_1_2_9_16_1","first-page":"13","article-title":"Circulating Cell\u2010Free DNA as Inflammatory Marker in Egyptian Psoriasis Patients","volume":"10","author":"Anani H. 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