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We used an experimental IgG <jats:styled-content style=\"fixed-case\">ELISA<\/jats:styled-content> test based on the recombinant antigen rEgAgB8\/1 cloned from <jats:italic><jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>chinococcus granulosus<\/jats:italic> to differentiate active from inactive\/cured <jats:styled-content style=\"fixed-case\">CE<\/jats:styled-content> infection, comparing its performance to that of a commercially available <jats:styled-content style=\"fixed-case\">ELISA<\/jats:styled-content> test used routinely in our hospital laboratory. Both tests were performed on sera from 88 patients with hepatic echinococcal cysts, grouped according to cyst stage based on ultrasonographical morphology, and on 17 patients surgically treated for echinococcosis and 18 patients with nonparasitic hepatic cysts included as controls. Tests\u2019 performances did not differ significantly, but the overall concordance between tests drastically dropped when groups were analysed separately. Further longitudinal studies should evaluate whether these discrepancies reflect the different ability of either test to predict the evolution of cysts over time. Although the recombinant\u2010AgB8\/1\u2010based <jats:styled-content style=\"fixed-case\">ELISA<\/jats:styled-content> test seems to have no clinical advantage over the commercially available <jats:styled-content style=\"fixed-case\">ELISA<\/jats:styled-content> test in the assessment of hepatic CE cyst viability, the easiness of production and reproducibility of high\u2010quality recombinant antigens makes rEgAgB8\/1 a valid candidate for use in <jats:styled-content style=\"fixed-case\">CE ELISA<\/jats:styled-content> diagnostic tests.<\/jats:p>","DOI":"10.1111\/pim.12050","type":"journal-article","created":{"date-parts":[[2013,7,8]],"date-time":"2013-07-08T15:40:20Z","timestamp":1373298020000},"page":"433-440","source":"Crossref","is-referenced-by-count":25,"title":["Recombinant AgB8\/1 <scp>ELISA<\/scp> test vs. commercially available IgG <scp>ELISA<\/scp> test in the diagnosis of cystic 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