{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:03:40Z","timestamp":1762542220854},"reference-count":53,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,2,18]],"date-time":"2014-02-18T00:00:00Z","timestamp":1392681600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasite Immunology"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>W. K. Yong and D. D. Heath published in 1979 a seminal paper in the first issue of <jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>arasite Immunology<\/jats:italic> describing their efforts to determine whether the arc 5 precipitin band, formed when test human serum is reacted against electrophoresed hydatid cyst fluid antigen, would be a suitable immunodiagnostic test for the identification of sheep infected with <jats:italic><jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>chinococcus granulosus<\/jats:italic>. Although they found antibodies to arc 5 in the sera of hydatid\u2010infected sheep, the sera of some sheep harbouring <jats:italic>Taenia ovis<\/jats:italic> and <jats:italic>T.\u00a0hydatigena<\/jats:italic> also precipitated the hydatid cyst fluid arc 5 antigen, so they concluded arc 5 antibodies were not suitable for the specific immunodiagnosis of <jats:italic>E.\u00a0granulosus<\/jats:italic> infection in sheep in <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ew <jats:styled-content style=\"fixed-case\">Z<\/jats:styled-content>ealand. Subsequent work has shown that the existence of multiple infections with different taeniid species, antigenic cross\u2010reactivity between these related parasites and the low level of specific antibody response to infection continue to hinder efforts to improve the diagnosis of hydatid infection in sheep and other natural intermediate hosts, thereby preventing the development of any practical test. In particular, the poor antibody response of ruminants to naturally acquired hydatid infection may prove an insurmountable barrier in future efforts to develop a reliable and accurate immunological test.<\/jats:p>","DOI":"10.1111\/pim.12072","type":"journal-article","created":{"date-parts":[[2013,8,23]],"date-time":"2013-08-23T14:20:57Z","timestamp":1377267657000},"page":"125-130","source":"Crossref","is-referenced-by-count":23,"title":["Immunodiagnosis of sheep infections with <i><scp>E<\/scp>chinococcus granulosus<\/i>: in 35\u00a0years where have we come?"],"prefix":"10.1111","volume":"36","author":[{"given":"D. P.","family":"McManus","sequence":"first","affiliation":[{"name":"Molecular Parasitology Laboratory Division of Infectious Diseases Queensland Institute of Medical Research Herston Qld Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,2,18]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3024.1979.tb00693.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"crossref","first-page":"617","DOI":"10.4269\/ajtmh.1976.25.617","article-title":"Evaluation of immunodiagnostic techniques for the detection of human hydatid cyst carriers in field studies","volume":"25","author":"Varela\u2010D\u00edaz VM","year":"1976","journal-title":"Am J Trop Med Hyg"},{"key":"e_1_2_5_4_1","first-page":"357","article-title":"Le diagnostique immunologique de l' echinococcose humaine","volume":"18","author":"Capron A","year":"1970","journal-title":"Pathol Biol"},{"key":"e_1_2_5_5_1","first-page":"130","volume-title":"Immunology of Parasitic Infections","author":"Kagan IG","year":"1976"},{"key":"e_1_2_5_6_1","first-page":"69","article-title":"Standardization of the immunoelectrophoresis test with whole and purified hydatid cyst fluid antigens for the diagnosis of human hydatidosis","volume":"17","author":"Guisantes JA","year":"1975","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"e_1_2_5_7_1","first-page":"20","volume-title":"Le Kyste Hydatique du Foie","author":"Capron A","year":"1967"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.2307\/3275647"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1971.20.569"},{"key":"e_1_2_5_10_1","first-page":"217","volume-title":"The Biology of Echinococcus and Hydatid Disease","author":"Rickard MD","year":"1986"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166-6851(87)90003-X"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166-6851(89)90149-7"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1989.40.377"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(91)90039-2"},{"key":"e_1_2_5_15_1","first-page":"355","volume-title":"Echinococcus and Hydatid Disease","author":"Lightowlers MW","year":"1995"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.10.6679"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.16.1.18-36.2003"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5288(18)31996-9"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2009.11.001"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(07)70134-2"},{"key":"e_1_2_5_21_1","first-page":"20","volume-title":"WHO\/OIE Manual on Echinococcosis in Humans and Animals: a Public Health Problem of Global Concern","author":"Pawlowski ZS","year":"2001"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-706X(02)00225-5"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.2006.00060.x"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e3866"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/101895"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(01)00442-3"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2006.08.022"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1984.tb07200.x"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5288(96)90082-X"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182002002044"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.1994.tb00480.x"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.140.23.605"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(03)00128-6"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2004.04.006"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2006.06.018"},{"key":"e_1_2_5_36_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X10000349"},{"key":"e_1_2_5_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(02)00308-4"},{"key":"e_1_2_5_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3024.1996.tb01029.x"},{"key":"e_1_2_5_39_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000784"},{"key":"e_1_2_5_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/icb.1980.33"},{"key":"e_1_2_5_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(81)90062-X"},{"key":"e_1_2_5_42_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000085310"},{"key":"e_1_2_5_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-308X(08)60356-5"},{"key":"e_1_2_5_44_1","first-page":"1","volume-title":"Echinococcus and Hydatid Disease","author":"Thompson RCA","year":"1995"},{"key":"e_1_2_5_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166-6851(92)90109-W"},{"key":"e_1_2_5_46_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182005007973"},{"key":"e_1_2_5_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2013.02.010"},{"key":"e_1_2_5_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166-6851(85)90068-4"},{"key":"e_1_2_5_49_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000422"},{"key":"e_1_2_5_50_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-13-55"},{"key":"e_1_2_5_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12031"},{"key":"e_1_2_5_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2006.02.002"},{"key":"e_1_2_5_53_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001897"},{"key":"e_1_2_5_54_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000771"}],"container-title":["Parasite Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpim.12072","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pim.12072","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T09:59:49Z","timestamp":1694599189000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pim.12072"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,18]]},"references-count":53,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["10.1111\/pim.12072"],"URL":"https:\/\/doi.org\/10.1111\/pim.12072","archive":["Portico"],"relation":{},"ISSN":["0141-9838","1365-3024"],"issn-type":[{"value":"0141-9838","type":"print"},{"value":"1365-3024","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,18]]}}}