{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T06:44:24Z","timestamp":1777963464670,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,6,13]],"date-time":"2016-06-13T00:00:00Z","timestamp":1465776000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasite Immunology"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>An oil\u2010based formulation of the <jats:styled-content style=\"fixed-case\">EG<\/jats:styled-content>95 vaccine to protect grazing animals against infection with <jats:italic>Echinococcus granulosus<\/jats:italic> was formulated in Argentina. The efficacy of the vaccine was monitored by serology in sheep and llama (<jats:italic>Lama glama<\/jats:italic>) and was compared to the serology in sheep previously published using a QuilA\u2010adjuvanted vaccine. Long\u2010term efficacy was also tested in sheep by challenging with <jats:italic>E. granulosus<\/jats:italic> eggs of the G1 strain 4 years after the beginning of the trial. The serological results for both sheep and llama were similar to those described previously, except that there was a more rapid response after the first vaccination. A third vaccination given after 1 year resulted in a transient boost in serology that lasted for about 12 months, which was similar to results previously described. Sheep challenged after 4 years with three vaccinations presented 84\u00b72% reduction of live cysts counts compared with control group, and after a fourth vaccination prior to challenge, this reduction was 94\u00b77%. The oil\u2010based vaccine appeared to be bio\u2010equivalent to the QuilA vaccine.<\/jats:p>","DOI":"10.1111\/pim.12325","type":"journal-article","created":{"date-parts":[[2016,4,22]],"date-time":"2016-04-22T23:03:57Z","timestamp":1461366237000},"page":"496-502","source":"Crossref","is-referenced-by-count":13,"title":["Serology and longevity of immunity against <i>Echinococcus granulosus<\/i> in sheep and llama induced by an oil\u2010based <scp>EG<\/scp>95 vaccine"],"prefix":"10.1111","volume":"38","author":[{"given":"T. V.","family":"Poggio","sequence":"first","affiliation":[{"name":"Centro de Virologia Animal Instituto de Ciencia y Tecnolog\u00eda \u201cDr. Cesar Milstein\u201d \u2013 CONICET Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Jensen","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n en Zoonosis Chubut Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Mossello","sequence":"additional","affiliation":[{"name":"Departamento Zooantroponosis Ministerio de Salud Chubut Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Iriarte","sequence":"additional","affiliation":[{"name":"Departamento Zooantroponosis Ministerio de Salud Chubut Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. 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