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Multiple experimental murine models for trypanosomosis have demonstrated inflammation\u2010dependent apoptosis of splenic follicular B (FoB) cells and the destruction of B\u2010cell memory against previously encountered pathogens. Here, we report that during murine infection with a chronic <jats:italic>T.\u00a0b.\u00a0gambiense<\/jats:italic> field isolate, FoB cells are retained. This coincided with reduced levels of IFN\u2010\u03b3 and TNF\u2010\u03b1 during the acute phase of the infection. This result suggests that in chronic infections with low virulent parasites, less inflammation is elicited and consequently no FoB cell destruction occurs.<\/jats:p>","DOI":"10.1111\/pim.12344","type":"journal-article","created":{"date-parts":[[2016,6,29]],"date-time":"2016-06-29T07:52:13Z","timestamp":1467186733000},"page":"642-647","source":"Crossref","is-referenced-by-count":12,"title":["Maintenance of B cells during chronic murine <i>Trypanosoma brucei gambiense<\/i> infection"],"prefix":"10.1111","volume":"38","author":[{"given":"J.","family":"Cnops","sequence":"first","affiliation":[{"name":"Laboratory of Cellular and Molecular Immunology Vrije Universiteit Brussel  Brussels Belgium"},{"name":"Structural Biology Research Center Vlaams Instituut voor Biotechnologie (VIB)  Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Kauffmann","sequence":"additional","affiliation":[{"name":"Laboratory of Cellular and Molecular Immunology Vrije 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