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Infection with <jats:italic>Anisakis<\/jats:italic> is associated with abdominal pain, nausea and diarrhoea and can lead to massive infiltration of eosinophils and formation of granulomas in the gastrointestinal tract if the larvae are not removed. Re\u2010infection leads to systemic allergic reactions such as urticarial or anaphylaxis in some individuals, making <jats:italic>Anisakis<\/jats:italic> an important source of hidden allergens in seafood. This review summarizes the immunopathology associated with <jats:italic>Anisakis<\/jats:italic> infection. Anisakiasis and gastroallergic reactions can be prevented by consuming only fish that has been frozen to \u221220\u00b0C to the core for at least 24\u00a0hours before preparation. Sensitization to <jats:italic>Anisakis<\/jats:italic> proteins can also occur, primarily due to occupational exposure to infested fish, and can lead to dermatitis, rhinoconjunctivitis or asthma. 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