{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T13:01:32Z","timestamp":1780837292520,"version":"3.54.1"},"reference-count":50,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,3,4]],"date-time":"2018-03-04T00:00:00Z","timestamp":1520121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007350","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["28236"],"award-info":[{"award-number":["28236"]}],"id":[{"id":"10.13039\/501100007350","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasite Immunology"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The aim of the present study was to evaluate associations between intestinal parasitic infection with intestinal and systemic inflammatory markers in school\u2010aged children with high rates of obesity. Plasma concentrations of C\u2010Reactive Protein (<jats:styled-content style=\"fixed-case\">CRP<\/jats:styled-content>), leptin, <jats:styled-content style=\"fixed-case\">TNF<\/jats:styled-content>\u2010\u03b1, <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20106 and <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201010 were measured as systemic inflammation markers and count of stool leukocytes as marker of intestinal inflammation in 291 children (6\u201010\u00a0years). Intestinal parasitic infection was measured by stool examination. Logistic regression analyses were performed to determine the odds of having high inflammatory markers for each parasite or group of parasites as compared to parasite\u2010free children while adjusting for sex, age, mother's educational level and percentage of body fat. The prevalence of soil\u2010transmitted helminths and intestinal protozoa infections was 12% and 36%, respectively. Parasitic infection was not associated with <jats:styled-content style=\"fixed-case\">CRP<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> IL<\/jats:styled-content>\u20106, <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201010 or <jats:styled-content style=\"fixed-case\">TNF<\/jats:styled-content>\u2010\u03b1. Children infected with <jats:italic>Ascaris lumbricoides<\/jats:italic> (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>: 5.91, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.97\u201017.70) and <jats:italic>Entamoeba coli<\/jats:italic> (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>: 8.46, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 2.85\u201025.14) were more likely to have higher stool leucocytes than parasite\u2010free children. Children with multiple infections (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>: 10.60, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 2.85\u201025.14) were more likely to have higher leptin concentrations than parasite\u2010free children. Intestinal parasitic infection was not associated with systemic inflammation, but was associated with intestinal inflammation. Having multiple infections were associated with higher leptin concentrations.<\/jats:p>","DOI":"10.1111\/pim.12518","type":"journal-article","created":{"date-parts":[[2018,1,24]],"date-time":"2018-01-24T14:35:18Z","timestamp":1516804518000},"source":"Crossref","is-referenced-by-count":27,"title":["Intestinal parasites: Associations with intestinal and systemic inflammation"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9825-8725","authenticated-orcid":false,"given":"G. A.","family":"Zavala","sequence":"first","affiliation":[{"name":"Facultad de Ciencias Naturales Universidad Aut\u00f3noma de Quer\u00e9taro  Quer\u00e9taro Mexico"},{"name":"Faculty of Earth &amp; Life Sciences Vrije Universiteit Amsterdam  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O. 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