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However, the research community faces limitations in its use due to the lack of immunological reagents and tools to study the immune system in this model. In this context, we proposed the validation of some important commercially anti\u2010mouse mAbs (CD4, TNF\u2010\u03b1, IFN\u2010\u03b3 and IL\u201010) and how this could be useful to evaluate a specific cellular immune response in\n                    <jats:italic>Leishmania<\/jats:italic>\n                    \u2010infected hamster using flow cytometry experiments. Our data demonstrated a cross\u2010reactivity between these anti\u2010mouse mAbs and hamster molecules that were herein studied. Beyond that, it was able to characterize the development of a specific cellular immune response through cytokine production in\n                    <jats:italic>L infantum<\/jats:italic>\n                    \u2010infected hamsters when compared to uninfected ones. These data not only aid the usage of hamsters as experimental model to investigate various infectious diseases, but they contribute to the design of novel approaches to further investigate the immunological mechanisms associated to pathogen infections.\n                  <\/jats:p>","DOI":"10.1111\/pim.12823","type":"journal-article","created":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T15:19:41Z","timestamp":1611415181000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Establishment of monoclonal antibodies to evaluate the cellular immunity in a hamster model of\n                    <i>L infantum<\/i>\n                    infection"],"prefix":"10.1111","volume":"43","author":[{"given":"L\u00edvia Mendes","family":"Carvalho","sequence":"first","affiliation":[{"name":"Laborat\u00f3rio de Imunopatologia N\u00facleo de Pesquisas em Ci\u00eancias Biol\u00f3gicas\/NUPEB Universidade Federal de Ouro Preto Ouro Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rory Cristiane Fortes","family":"de Brito","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Imunopatologia N\u00facleo de Pesquisas em Ci\u00eancias Biol\u00f3gicas\/NUPEB Universidade Federal de Ouro Preto Ouro Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miri\u00e3 Rodrigues","family":"Gusm\u00e3o","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Imunopatologia N\u00facleo de Pesquisas em Ci\u00eancias Biol\u00f3gicas\/NUPEB Universidade Federal de Ouro Preto Ouro Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo Dian","family":"de Oliveira Aguiar\u2010Soares","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Imunopatologia N\u00facleo de Pesquisas em Ci\u00eancias Biol\u00f3gicas\/NUPEB Universidade Federal de Ouro Preto Ouro Preto Brazil"},{"name":"Departamento de An\u00e1lises Cl\u00ednicas Escola de Farm\u00e1cia Universidade Federal de Ouro Preto Ouro Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre Barbosa","family":"Reis","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Imunopatologia N\u00facleo de Pesquisas em Ci\u00eancias Biol\u00f3gicas\/NUPEB Universidade Federal de Ouro Preto Ouro Preto Brazil"},{"name":"Instituto Nacional de Ci\u00eancia e Tecnologia em Doen\u00e7as Tropicais (INCT\u2010DT) Salvador Brazil"},{"name":"Departamento de An\u00e1lises Cl\u00ednicas Escola de Farm\u00e1cia Universidade Federal de Ouro Preto Ouro Preto Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5281-3263","authenticated-orcid":false,"given":"Bruno Mendes","family":"Roatt","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Imunopatologia N\u00facleo de Pesquisas em Ci\u00eancias Biol\u00f3gicas\/NUPEB Universidade Federal de Ouro Preto Ouro Preto Brazil"},{"name":"Instituto Nacional de Ci\u00eancia e Tecnologia em Doen\u00e7as Tropicais (INCT\u2010DT) Salvador Brazil"},{"name":"Departamento de Ci\u00eancias Biol\u00f3gicas Insituto de Ci\u00eancias Exatas e Biol\u00f3gicas Universidade Federal de Ouro Preto Ouro Preto 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