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Antibody response to specific malaria vaccine candidates (MVC) has been associated with a decreased risk of clinical malaria and its outcomes. We studied\n                    <jats:italic>Plasmodium falciparum<\/jats:italic>\n                    (\n                    <jats:italic>Pf<\/jats:italic>\n                    ) and\n                    <jats:italic>Schistosoma haematobium<\/jats:italic>\n                    (\n                    <jats:italic>Sh<\/jats:italic>\n                    ) infections and factors that could influence antibody responses to MVC in pregnant women. A total of 337 pregnant women receiving antenatal care (ANC) and 139 for delivery participated in this study.\n                    <jats:italic>Pf<\/jats:italic>\n                    infection was detected by qPCR and\n                    <jats:italic>Sh<\/jats:italic>\n                    infection using urine filtration method. Antibody levels against CSP, AMA\u20101, GLURP\u2010R0, VAR2CSA and Pfs48\/45 MVC were quantified by ELISA. Multivariable linear regression models identified factors associated with the modulation of antibody responses. The prevalence of\n                    <jats:italic>Pf<\/jats:italic>\n                    and\n                    <jats:italic>Sh<\/jats:italic>\n                    infections was 27% and 4% at ANC and 7% and 4% at delivery.\n                    <jats:italic>Pf<\/jats:italic>\n                    infection, residing in Adidome and multigravidae were positively associated with specific IgG response to CSP, AMA\u20101, GLURP\u2010R0 and VAR2CSA. ITN use and IPTp were negatively associated with specific IgG response to GLURP\u2010R0 and Pfs48\/45. There was no association between\n                    <jats:italic>Sh<\/jats:italic>\n                    infection and antibody response to MVC at ANC or delivery.\n                    <jats:italic>Pf<\/jats:italic>\n                    infections in pregnant women were positively associated with antibody response to CSP, GLURP\u2010R0 and AMA\u20101. Antibody response to GLURP\u2010R0 and Pfs48\/45 was low for IPTp and ITN users. This could indicate a lower exposure to\n                    <jats:italic>Pf<\/jats:italic>\n                    infection and low malaria prevalence observed at delivery.\n                  <\/jats:p>","DOI":"10.1111\/pim.13027","type":"journal-article","created":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T08:18:20Z","timestamp":1712564300000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Antibody response to malaria vaccine candidates in pregnant women with\n                    <i>Plasmodium falciparum<\/i>\n                    and\n                    <i>Schistosoma haematobium<\/i>\n                    infections"],"prefix":"10.1111","volume":"46","author":[{"given":"Naa Adjeley","family":"Frempong","sequence":"first","affiliation":[{"name":"Department of Clinical Microbiology School of Medical Sciences, Kwame Nkrumah University of Science and Technology  Kumasi Ghana"},{"name":"Parasitology Department, Noguchi Memorial Institute for Medical Research, College of Health Sciences University of Ghana  Legon Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atikatou","family":"Mama","sequence":"additional","affiliation":[{"name":"Inserm U 1016, Institut Cochin, Universit\u00e9 de  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bright","family":"Adu","sequence":"additional","affiliation":[{"name":"Immunology Department, Noguchi Memorial Institute for Medical Research, College of Health Sciences University of Ghana  Legon Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5483-9985","authenticated-orcid":false,"given":"Kwadwo Asamoah","family":"Kusi","sequence":"additional","affiliation":[{"name":"Immunology Department, Noguchi Memorial Institute for Medical Research, College of Health Sciences University of Ghana  Legon Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael F.","family":"Ofori","sequence":"additional","affiliation":[{"name":"Immunology Department, Noguchi Memorial Institute for Medical Research, College of Health Sciences University of Ghana  Legon Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charity","family":"Ahiabor","sequence":"additional","affiliation":[{"name":"Science Laboratory Department Accra Technical University  Accra Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William K.","family":"Anyan","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology School of Medical Sciences, Kwame Nkrumah University of Science and Technology  Kumasi Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex Yaw","family":"Debrah","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Kwame Nkrumah University of Science and Technology  Kumasi Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abraham A.","family":"Anang","sequence":"additional","affiliation":[{"name":"Institute for Environment and Sanitation Studies (IESS) University of Ghana  Legon Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicaise T.","family":"Ndam","sequence":"additional","affiliation":[{"name":"UMR 216 MERIT, IRD Universit\u00e9 Paris Cit\u00e9  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Courtin","sequence":"additional","affiliation":[{"name":"UMR 216 MERIT, IRD Universit\u00e9 Paris Cit\u00e9  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,8]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"WHO.Malaria. 2022 [cited 2022 Apr 6]. 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