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Thus, both can be considered potential targets for understanding regulatory processes in chronic inflammation in patients with schistosomiasis. Populations in endemic areas receive mass and indiscriminate praziquantel treatment, and yet patients often have a history of multiple infections. To investigate the regulatory and prognostic capacity of miR\u201010 and IFNG in patient immunity, we evaluated the expression of miR\u201010a and IFNG as biomarkers of inflammation and their correlation with praziquantel treatment. miR\u201010a did not present evidence as a biomarker of inflammation in the therapeutic follow\u2010up in schistosomiasis. However, the levels of\n                    <jats:italic>IFNG<\/jats:italic>\n                    expression were significantly higher before treatment.\n                  <\/jats:p>","DOI":"10.1111\/pim.70011","type":"journal-article","created":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T08:09:47Z","timestamp":1749110987000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Analysis of\n                    <scp>miR<\/scp>\n                    \u201010a and\n                    <scp>\n                      <i>IFNG<\/i>\n                    <\/scp>\n                    Expression Before and After Treatment for Chronic\n                    <i>Schistosomiasis mansoni<\/i>"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1181-5542","authenticated-orcid":false,"given":"D\u00e9bora Nascimento","family":"da N\u00f3brega","sequence":"first","affiliation":[{"name":"Instituto Aggeu Magalh\u00e3es (IAM\/Fiocruz)  Recife Pernambuco Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Virg\u00ednia Matos S\u00e1","family":"Barreto","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio Maur\u00edcio de Nassau (UNINASSAU)  Recife Pernambuco Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta","family":"dos Santos Souza","sequence":"additional","affiliation":[{"name":"Instituto Aggeu Magalh\u00e3es (IAM\/Fiocruz)  Recife Pernambuco Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kleyton Palmeira","family":"do \u00d3","sequence":"additional","affiliation":[{"name":"Instituto Aggeu Magalh\u00e3es (IAM\/Fiocruz)  Recife Pernambuco Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raul Em\u00eddio","family":"de Lima","sequence":"additional","affiliation":[{"name":"Instituto Aggeu Magalh\u00e3es (IAM\/Fiocruz)  Recife Pernambuco Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana L\u00facia Coutinho","family":"Domingues","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pernambuco, Hospital das Cl\u00ednicas  Recife Pernambuco Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edmundo Pessoa","family":"Lopes","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pernambuco, Hospital das Cl\u00ednicas  Recife Pernambuco Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clarice Neuenschwander Lins","family":"de Morais","sequence":"additional","affiliation":[{"name":"Instituto Aggeu Magalh\u00e3es (IAM\/Fiocruz)  Recife Pernambuco Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elainne Christine de Souza","family":"Gomes","sequence":"additional","affiliation":[{"name":"Instituto Aggeu Magalh\u00e3es (IAM\/Fiocruz)  Recife Pernambuco Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luydson Richardson Silva","family":"Vasconcelos","sequence":"additional","affiliation":[{"name":"Instituto Aggeu Magalh\u00e3es (IAM\/Fiocruz)  Recife Pernambuco Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,5]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"World Health Organization \u201cProgress Report 2001\u20132011 and Strategic Plan 2012\u20132020 \u201d(2013) accessed August 15 2022 https:\/\/apps.who.int\/iris\/handle\/10665\/78074."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762010000400040"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0000000000000312"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2020.105668"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.00061"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762007005000002"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-706X(00)00127-3"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2012.11-0204"},{"issue":"2","key":"e_1_2_10_10_1","first-page":"3","article-title":"Modulation of Mice Immune Responses Against Schistosoma mansoni Infection With Anti\u2010Schistosomiasis Drugs: Role of Interleukin\u20104 and Interferon\u2010Gamma","volume":"16","author":"Sharaf O. 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