{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T01:56:12Z","timestamp":1780451772083,"version":"3.54.1"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,5,28]],"date-time":"2013-05-28T00:00:00Z","timestamp":1369699200000},"content-version":"vor","delay-in-days":27,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathology International"],"published-print":{"date-parts":[[2013,5]]},"abstract":"Inflammatory pseudotumor (IPT<\/jats:styled-content>)\u2010like follicular dendritic cell (FDC<\/jats:styled-content>) sarcoma is a rare neoplasm typically occurring in the spleen or liver. We present six cases of EBV<\/jats:styled-content>+<\/jats:sup> IPT<\/jats:styled-content>\u2010like FDC<\/jats:styled-content> sarcoma of the spleen among K<\/jats:styled-content>oreans along with their clinicopathologic features and IHC<\/jats:styled-content> results. Most patients presented with an asymptomatic, incidentally detected single splenic mass and were successfully managed by splenectomy alone. Concomitant disease was found in one case, showing EBV<\/jats:styled-content>+<\/jats:sup> gastric carcinoma with lymphoid\u2010rich stroma. Histologic features showed fibro\u2010inflammatory lesions that were often accompanied by necrosis and epithelioid histiocytic collection, which are barely distinguishable from IPT<\/jats:styled-content>. Tumor cells did not frequently express conventional FDC<\/jats:styled-content> markers, including CD<\/jats:styled-content>21 (3\/6 positive cases), clusterin (4\/6), and D<\/jats:styled-content>2\u201040 (2\/6), but showed uniform positivity for smooth muscle actin (SMA<\/jats:styled-content>). Noticeably, significant numbers of IgG4<\/jats:styled-content>+<\/jats:sup> plasma cells were found within all six tumors. We suggest that the diagnosis of IPT<\/jats:styled-content>\u2010like FDC<\/jats:styled-content> sarcoma should be made by the application of a panel of FDC<\/jats:styled-content> markers, and CD<\/jats:styled-content>21 negativity or SMA<\/jats:styled-content> positivity cannot be the criterion for exclusion of IPT<\/jats:styled-content>\u2010like FDC<\/jats:styled-content> sarcoma. Relationship of IPT<\/jats:styled-content>\u2010like FDC<\/jats:styled-content> sarcoma of the spleen and IgG4<\/jats:styled-content>\u2010related sclerosing disease should be investigated in further studies.<\/jats:p>","DOI":"10.1111\/pin.12057","type":"journal-article","created":{"date-parts":[[2013,5,29]],"date-time":"2013-05-29T06:57:09Z","timestamp":1369810629000},"page":"245-251","source":"Crossref","is-referenced-by-count":74,"title":["Inflammatory pseudotumor\u2010like follicular dendritic cell sarcoma of the spleen: A report of six cases with increased IgG4<\/scp>\u2010positive plasma cells"],"prefix":"10.1111","volume":"63","author":[{"given":"Ji\u2010Young","family":"Choe","sequence":"first","affiliation":[{"name":"Department of Pathology Seoul National University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heounjeong","family":"Go","sequence":"additional","affiliation":[{"name":"Department of Pathology Seoul National 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