{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:17:58Z","timestamp":1787015878786,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,5,28]],"date-time":"2013-05-28T00:00:00Z","timestamp":1369699200000},"content-version":"vor","delay-in-days":27,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathology International"],"published-print":{"date-parts":[[2013,5]]},"abstract":"\n We report an atypical case of non\u2010sebaceous lymphadenoma (\n NSL<\/jats:styled-content>\n ) of the parotid gland showing serous acinic cell differentiation.\n NSL<\/jats:styled-content>\n is a rare benign salivary gland tumor with intermingled lymphoid and epithelial tissues without sebaceous differentiation. Since the first description of a case designated by\n A<\/jats:styled-content>\n uclair\n et\u2009al<\/jats:italic>\n . as \u2018non\u2010sebaceous lymphadenoma\u2019 in 1991, to our best knowledge, only 37 cases have been reported, and no differentiation of tumor cells into serous acinic cell lineage has been described so far. In this paper, we present a case of\n NSL<\/jats:styled-content>\n with serous acinic cell differentiation. The patient was a 78\u2010year\u2010old female with the complaint of a painless mass in the left parotid gland. The surgically resected tumor was encapsulated and measured 13 \u00d7 9 \u00d7 9\u2009mm. Histologically, the tumor had the features of\n NSL<\/jats:styled-content>\n , and an unusual finding of this case was the presence of epithelial cells with serous acinic cell differentiation. Dense cytoplasm packed with basophilic granules in those cells was positive in periodic acid\n S<\/jats:styled-content>\n chiff reaction after diastase digestion (\n D<\/jats:styled-content>\n \u2010\n PAS<\/jats:styled-content>\n ), which was compatible with the feature of serous acinic cell differentiation. Possible differentiation of the epithelial component into serous acinic cell in this rare entity is warranted to avoid confusion in the diagnosis.\n <\/jats:p>","DOI":"10.1111\/pin.12061","type":"journal-article","created":{"date-parts":[[2013,5,29]],"date-time":"2013-05-29T02:57:09Z","timestamp":1369796229000},"page":"272-276","source":"Crossref","is-referenced-by-count":10,"title":["Non\u2010sebaceous lymphadenoma of the salivary gland with serous acinic cell differentiation, a first case report in the literature"],"prefix":"10.1111","volume":"63","author":[{"given":"Aya","family":"Ishii","sequence":"first","affiliation":[{"name":"Department of Pathology Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroo","family":"Kawano","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinsuke","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Division of Surgical Pathology Yamaguchi University Hospital Ube Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohei","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuya","family":"Nakamoto","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinobu","family":"Hirose","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Yamashita","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shojiroh","family":"Morinaga","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology Kitasato Institute Hospital Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiji","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Department of Pathology Yamaguchi University Graduate School of Medicine Ube Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,5,28]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.2002.01528.x"},{"key":"e_1_2_5_3_1","first-page":"269","volume-title":"World Health Organization Classification of 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