{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:10:04Z","timestamp":1787760604142,"version":"build-2784847793"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,6,26]],"date-time":"2014-06-26T00:00:00Z","timestamp":1403740800000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathology International"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:p>\n                    Stenosing flexor tenosynovitis, trigger finger, is a common clinical disorder causing painful locking or contracture of the involved digits, and most instances are idiopathic. This problem is generally caused by a size mismatch between the swollen flexor tendon and the thickened first annular pulley. Although hypertrophic pulleys have been histologically and ultrasonographically detected, little is known about the histopathology of the tenosynovium covering the tendons of trigger fingers. We identified chondrocytoid cells that produced hyaluronic acid in 23 (61%) fingers and hypocellular collagen matrix in 32 (84%) fingers around the tenosynovium among 38 specimens of tenosynovium from patients with trigger fingers. These chondrocytoid cells expressed the synovial\n                    <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>\n                    cell marker\n                    <jats:styled-content style=\"fixed-case\">CD44<\/jats:styled-content>\n                    , but not the chondrocyte marker\n                    <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>\n                    \u2010100 protein. The incidence of these findings was much higher than that of conventional findings of synovitis, such as inflammatory infiltrate (37%), increased vascularity (37%), hyperplasia of synovial lining cells (21%), or fibrin exudation (5%). We discovered the following distinctive histopathological features of trigger finger: hyaluronic acid\u2010producing chondrocytoid cells originated from fibroblastic synovial\n                    <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>\n                    cells, and a hypocellular collagen matrix surrounding the tenosynovium. Thus, an edematous extracellular matrix with active hyaluronic acid synthesis might increase pressure under the pulley and contribute to the progression of stenosis.\n                  <\/jats:p>","DOI":"10.1111\/pin.12168","type":"journal-article","created":{"date-parts":[[2014,6,26]],"date-time":"2014-06-26T05:56:23Z","timestamp":1403762183000},"page":"276-282","source":"Crossref","is-referenced-by-count":27,"title":["Histopathology of tenosynovium in trigger fingers"],"prefix":"10.1111","volume":"64","author":[{"given":"Kazuyoshi","family":"Uchihashi","sequence":"first","affiliation":[{"name":"Department of Pathology and Microbiology Faculty of Medicine, Saga University  Saga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyuki","family":"Tsuruta","sequence":"additional","affiliation":[{"name":"Tsuruta Orthopaedic Clinic  Ogi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroko","family":"Mine","sequence":"additional","affiliation":[{"name":"Tsuruta Orthopaedic Clinic  Ogi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigehisa","family":"Aoki","sequence":"additional","affiliation":[{"name":"Department of Pathology and Microbiology Faculty of Medicine, Saga University  Saga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aki","family":"Nishijima\u2010Matsunobu","sequence":"additional","affiliation":[{"name":"Department of Pathology and Microbiology Faculty of Medicine, Saga University  Saga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihoko","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Pathology and Microbiology Faculty of Medicine, Saga University  Saga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akio","family":"Kuraoka","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Physiology Faculty of Medicine, Saga University  Saga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuji","family":"Toda","sequence":"additional","affiliation":[{"name":"Department of Pathology and Microbiology Faculty of Medicine, Saga University  Saga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,6,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.phm.0000184236.81774.b5"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1753193411421853"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2005.10.013"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jus.2012.02.002"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1710980305"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2009.05.015"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0363-5023(90)90149-L"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780370210"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.a.20331"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.53.11.729"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2010.02511.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2012.09.001"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00267036"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00270244"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2008.27.10.1407"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0363-5023(91)90200-U"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhse.2007.06.002"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0363-5023(98)80009-9"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830221036"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.3109\/02844317709025518"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2013.03.005"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1142\/S0218810412500025"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2009.04.011"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2010.02.010"}],"container-title":["Pathology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpin.12168","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pin.12168","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T15:31:37Z","timestamp":1696001497000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pin.12168"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":24,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1111\/pin.12168"],"URL":"https:\/\/doi.org\/10.1111\/pin.12168","archive":["Portico"],"relation":{},"ISSN":["1320-5463","1440-1827"],"issn-type":[{"value":"1320-5463","type":"print"},{"value":"1440-1827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6]]}}}