{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T05:31:31Z","timestamp":1771651891213,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,3,27]],"date-time":"2015-03-27T00:00:00Z","timestamp":1427414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathology International"],"published-print":{"date-parts":[[2015,7]]},"abstract":"Medullary cystic kidney disease (MCKD<\/jats:styled-content>) is a progressive tubulointerstitial nephropathy, and it leads to end\u2010stage kidney disease (ESKD<\/jats:styled-content>). It is an autosomal dominant inherited disease, and is categorized into two types according to the localizing chromosome and timing of ESKD<\/jats:styled-content> onset. Its pathogenesis has not been revealed clearly, thus accumulation of the cases is very valuable. We report here the first reported case of MCKD<\/jats:styled-content> with kidney enlargement complicated by IgA<\/jats:styled-content> nephropathy. A 70\u2010year\u2010old male was admitted to our hospital because of renal dysfunction and bilateral kidney enlargement. He was diagnosed as having MCKD<\/jats:styled-content> complicated by IgA<\/jats:styled-content> nephropathy (IgA<\/jats:styled-content>\u2010N<\/jats:styled-content>) by renal biopsy. We speculated that he had MCKD<\/jats:styled-content> type 1 on the basis of the late onset of renal failure and no significant evidence of mutation in the UMOD<\/jats:styled-content><\/jats:italic> gene that is associated with MCKD<\/jats:styled-content> type 2. Thereafter, his kidney function decreased progressively and he started to receive hemodialysis. This is an interesting case of MCKD1<\/jats:styled-content> in terms of its sporadic nature, kidney enlargement, and complication of IgA<\/jats:styled-content>\u2010N<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/pin.12292","type":"journal-article","created":{"date-parts":[[2015,3,27]],"date-time":"2015-03-27T22:22:45Z","timestamp":1427494965000},"page":"379-382","source":"Crossref","is-referenced-by-count":3,"title":["A case of sporadic medullary cystic kidney disease type 1 (MCKD1<\/scp>) with kidney enlargement complicated by IgA<\/scp> nephropathy"],"prefix":"10.1111","volume":"65","author":[{"given":"Taihei","family":"Suzuki","sequence":"first","affiliation":[{"name":"Division of Nephrology Department of Medicine Showa University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Iyoda","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Medicine Showa University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Yamaguchi's Pathology Laboratory Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takanori","family":"Shibata","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Medicine Showa University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,3,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/7.5.905"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2543"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(03)00829-1"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004670000518"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.2741\/2999"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pap.0000201831.77472.d3"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002619900423"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.5301\/jn.5000151"},{"key":"e_1_2_6_10_1","first-page":"316","article-title":"Nephronophthisis\u2010medullary cystic kidney disease: From bedside to bench and back again","volume":"14","author":"Scolari F","year":"2003","journal-title":"Saudi J Kidney Dis Transpl"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfs505"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2013.07.027"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.49.2722"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2009.09.031"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-008-0066-1"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V651354"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000167662"}],"container-title":["Pathology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpin.12292","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pin.12292","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T17:01:29Z","timestamp":1695574889000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pin.12292"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,27]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["10.1111\/pin.12292"],"URL":"https:\/\/doi.org\/10.1111\/pin.12292","archive":["Portico"],"relation":{},"ISSN":["1320-5463","1440-1827"],"issn-type":[{"value":"1320-5463","type":"print"},{"value":"1440-1827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,27]]}}}