{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T16:16:35Z","timestamp":1787847395147,"version":"build-2784847793"},"reference-count":9,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,3,23]],"date-time":"2017-03-23T00:00:00Z","timestamp":1490227200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathology International"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:sec><jats:label\/><jats:p>Prominent cyst formation is an unusual feature of liposarcoma. We report here a case of dedifferentiated liposarcoma with huge cystic change without preoperative chemo\u2010 or radiation therapy. The lesion arose in the retroperitoneum juxtaposed to the right kidney of a 67\u2010year\u2010old woman. She underwent a surgical removal of the retroperitoneal cyst. The cystic tumor contained 1600\u2009mL of old bloody fluid, and its wall was composed of edematous, inflamed or sclerosing fibrous tissue with fatty tissue containing abundant atypical stromal cells, which were immunohistochemically positive for MDM2 and CDK4, and demonstrated <jats:italic>MDM2<\/jats:italic> gene amplification by fluorescence <jats:italic>in situ<\/jats:italic> hybridization. The wall was contiguous to an atypical lipomatous nodule located in the mesentery. The following surgical specimens of the right hemicolectomy and right nephrectomy revealed atypical cells infiltrating into the subserosa of the colon and the perirenal fat tissue or that in the renal sinus. This case indicates that well differentiated or dedifferentiated liposarcoma should be also considered as a differential diagnosis of perirenal cystic mass.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pin.12525","type":"journal-article","created":{"date-parts":[[2017,3,24]],"date-time":"2017-03-24T11:47:50Z","timestamp":1490356070000},"page":"264-268","source":"Crossref","is-referenced-by-count":7,"title":["Retroperitoneal dedifferentiated liposarcoma with huge cystic degeneration: A case report"],"prefix":"10.1111","volume":"67","author":[{"given":"Kazuyoshi","family":"Uchihashi","sequence":"first","affiliation":[{"name":"Department of Pathology &amp; Oncology School of Medicine University of Occupational and Environmental Health Kitakyushu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsuji","family":"Matsuyama","sequence":"additional","affiliation":[{"name":"Department of Pathology &amp; Oncology School of Medicine University of Occupational and Environmental Health Kitakyushu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eisuke","family":"Shiba","sequence":"additional","affiliation":[{"name":"Department of Pathology &amp; Oncology School of Medicine University of Occupational and Environmental Health Kitakyushu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshizo","family":"Kimura","sequence":"additional","affiliation":[{"name":"Department of Pathology St. Mary's Hospital Kurume Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiro","family":"Ogata","sequence":"additional","affiliation":[{"name":"Department of Surgery St. Mary's Hospital Kurume Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Yabuki","sequence":"additional","affiliation":[{"name":"Department of Pathology &amp; Oncology School of Medicine University of Occupational and Environmental Health Kitakyushu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Harada","sequence":"additional","affiliation":[{"name":"Department of Pathology &amp; Oncology School of Medicine University of Occupational and Environmental Health Kitakyushu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chisachi","family":"Kubo","sequence":"additional","affiliation":[{"name":"Department of Pathology &amp; Oncology School of Medicine University of Occupational and Environmental Health Kitakyushu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yojiro","family":"Tsuda","sequence":"additional","affiliation":[{"name":"Department of Pathology &amp; Oncology School of Medicine University of Occupational and Environmental Health Kitakyushu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mao","family":"Jotatsu","sequence":"additional","affiliation":[{"name":"Department of Pathology &amp; Oncology School of Medicine University of Occupational and Environmental Health Kitakyushu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Hisaoka","sequence":"additional","affiliation":[{"name":"Department of Pathology &amp; Oncology School of Medicine University of Occupational and Environmental Health Kitakyushu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,23]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"484","volume-title":"Liposarcoma. Enzinger and Weiss's soft tissue tumors","author":"Goldblum JR","year":"2013"},{"key":"e_1_2_6_3_1","first-page":"39","volume-title":"World Health Organization Classification of Tumours of Soft Tissue and Bone","author":"Dei Tos AP","year":"2013"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-11-305"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr\u20102015\u2010211218"},{"key":"e_1_2_6_6_1","first-page":"491","article-title":"Perinephric liposarcoma mimicking cystic renal tumor","volume":"93","author":"Horiguchi A","year":"2002","journal-title":"Nihon Hinyokika Gakkai Zasshi"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.245045017"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-015-0016-2"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2015.10.039"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199703000-00002"}],"container-title":["Pathology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpin.12525","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/pin.12525","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T22:36:06Z","timestamp":1696199766000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/pin.12525"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,23]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["10.1111\/pin.12525"],"URL":"https:\/\/doi.org\/10.1111\/pin.12525","archive":["Portico"],"relation":{},"ISSN":["1320-5463","1440-1827"],"issn-type":[{"value":"1320-5463","type":"print"},{"value":"1440-1827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,23]]}}}