{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T23:18:37Z","timestamp":1792451917242,"version":"4.5.0"},"reference-count":19,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,4,25]],"date-time":"2018-04-25T00:00:00Z","timestamp":1524614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pathology International"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec><jats:label\/><jats:p>Both glandular papilloma (GP) and sclerosing pneumocytoma (SP) are rare tumors in the lung. We herein report an extremely rare case of coexistence of these two uncommon tumors. The patient was a 40\u2010year\u2010old Japanese woman with no chief complaint. A solitary nodule of the lung was detected using chest computed tomography. The transbronchial biopsy revealed that the tumor histologically corresponded to GP. The patient subsequently underwent partial resection of the right upper lobe. Histological examination of the resected specimens further revealed that the mass contained two different and independent elements and displayed typically histological features of GP and SP. Molecular analysis further revealed the presence of <jats:italic>BRAF<\/jats:italic> V600E and <jats:italic>AKT1<\/jats:italic> E17K mutations in GP, whereas only <jats:italic>AKT1<\/jats:italic> mutation was detected in SP. To our knowledge, this is the first case of coexistence of GP and SP in the bronchiole harboring common <jats:italic>AKT1<\/jats:italic> mutation and different <jats:italic>BRAF<\/jats:italic> V600E mutational status.<\/jats:p><\/jats:sec>","DOI":"10.1111\/pin.12677","type":"journal-article","created":{"date-parts":[[2018,4,26]],"date-time":"2018-04-26T04:34:40Z","timestamp":1524717280000},"page":"425-430","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Coexistence of glandular papilloma and sclerosing pneumocytoma in the bronchiole"],"prefix":"10.1111","volume":"68","author":[{"given":"Yuko","family":"Kitawaki","sequence":"first","affiliation":[{"name":"Department of Anatomic Pathology Tohoku University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiyoshi","family":"Fujishima","sequence":"additional","affiliation":[{"name":"Division of Pathology Tohoku University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinji","family":"Taniuchi","sequence":"additional","affiliation":[{"name":"Division of Pathology Tohoku University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryoko","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology Tohoku University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Division of Pathology Faculty of Medicine Tohoku Medical and Pharmaceutical University Sendai"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryoko","family":"Sato","sequence":"additional","affiliation":[{"name":"Division of Pathology Tohoku University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yayoi","family":"Aoyama","sequence":"additional","affiliation":[{"name":"Division of Pathology Tohoku University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiaki","family":"Onodera","sequence":"additional","affiliation":[{"name":"Division of Pathology Tohoku University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoko","family":"Inoshita","sequence":"additional","affiliation":[{"name":"Department of Pathology Toranomon Hospital Tokyo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Matsuda","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Tohoku University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mika","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Research Division for Development of Anti\u2010Infective Agents Institute of Development, Aging and Cancer Tohoku University Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hironobu","family":"Sasano","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology Tohoku University Graduate School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,4,25]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"World Health Organization Classification of Tumours Pathology and Genetics of Tumours of the Lung, Pleura, Thymus, and Heart","author":"Travis WD","year":"2004"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2012.09.007"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-12-149"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00292-012-1725-2"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40064-016-3493-6"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e3182468d06"},{"key":"e_1_2_6_8_1","first-page":"964","article-title":"Ciliated muconodular papillary tumor of the peripheral lung: Benign or malignant? 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