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A 21\u2010year\u2010old woman who had liver transplantation for post\u2010Kasai biliary atresia was recently referred for post\u2010transplant biliary stricture. Her transplantation was performed at the age of 6 years using the whole liver graft from a 10\u2010year\u2010old donor and choledocho\u2010jejunostomy. The post\u2010transplant course was uneventful in the first 15 years until she presented with obstructive jaundice. The stricture was located at the level of the hepaticojejunostomy, and required percutaneous transhepatic drainage and bile duct dilatation. She underwent an exploratory laparotomy, which suggested a neoplastic process widely involving the extrahepatic and intrahepatic large bile ducts. The histological examination of the resected extrahepatic bile duct confirmed infiltrating moderately differentiated adenocarcinoma. Molecular tests of multiple short tandem repeat loci confirmed the donor origin of the tumor. After four cycles of chemotherapy with gemicitabine and cisplatin, she is currently on radiotherapy in view of potential re\u2010transplantation. <jats:italic>De novo<\/jats:italic>, post\u2010transplant cholangiocarcinoma of graft origin is extremely uncommon with only three other cases reported. Two were associated with recurrent primary sclerosing cholangitis, and all had choledocho\u2010jejunostomy at the time of transplantation.<\/jats:p>","DOI":"10.1111\/pin.12944","type":"journal-article","created":{"date-parts":[[2020,4,30]],"date-time":"2020-04-30T04:15:38Z","timestamp":1588220138000},"page":"563-567","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["<i>De novo<\/i> perihilar cholangiocarcinoma arising in the allograft liver 15 years post\u2010transplantation for biliary atresia"],"prefix":"10.1111","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8370-6508","authenticated-orcid":false,"given":"Yoh","family":"Zen","sequence":"first","affiliation":[{"name":"Institute of Liver Studies King's College Hospital  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parthi","family":"Srinivasan","sequence":"additional","affiliation":[{"name":"Institute of Liver Studies 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