{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T14:22:07Z","timestamp":1775053327694,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,7,15]],"date-time":"2020-07-15T00:00:00Z","timestamp":1594771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pathology International"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:p>The histology of basaloid squamous cell carcinoma (BSCC) can resemble that of adenoid cystic carcinoma (AdCC). Herein, we report two cases of BSCC with adenoid cystic\u2010like features (BSCC\u2010AdC). We collected cases of AdCC and BSCC of the head and neck region, extracted two cases with unusual histology, and reexamined them histologically and immunohistochemically. Case 1 involved an 81\u2010year\u2010old Japanese male, who had an elastic\u2010hard mass on the left side of his tongue, and a biopsy examination suggested AdCC. Case 2 involved a 63\u2010year\u2010old Japanese male, who had a polypoid mass on his right hypopharynx. He was diagnosed with AdCC with high\u2010grade transformation. Histologically, atypical cells in a myxoid stroma, which exhibited trabecular, nest\u2010like, and\/or cribriform growth patterns, and necrosis were observed in both cases. Case 2 displayed more marked cellular atypia than Case 1. Immunohistochemically, the tumor cells were diffusely positive for cytokeratin 5\/6, p63\/p40, SRY\u2010related HMG\u2010box 10 and Ki\u201067, but negative for other myoepithelial markers and p16. Finally, both cases were rediagnosed as BSCC\u2010AdC. It is known that esophageal BSCC displays adenoid cystic\u2010like features, and BSCC\u2010AdC also sometimes occurs in the head and neck region. Clinicians should carefully differentiate BSCC\u2010AdC from AdCC of the minor salivary glands and human papillomavirus\u2010related carcinoma.<\/jats:p>","DOI":"10.1111\/pin.12986","type":"journal-article","created":{"date-parts":[[2020,7,15]],"date-time":"2020-07-15T10:51:33Z","timestamp":1594810293000},"page":"767-774","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Basaloid squamous cell carcinoma with adenoid cystic\u2010like features of the head and neck region: A report of two cases"],"prefix":"10.1111","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3482-7447","authenticated-orcid":false,"given":"Kimihide","family":"Kusafuka","sequence":"first","affiliation":[{"name":"Department of Pathology Shizuoka General Hospital  Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruna","family":"Yagi","sequence":"additional","affiliation":[{"name":"Department of Pathology Shizuoka General Hospital  Shizuoka Japan"},{"name":"Department of Regeneration and Infection Pathology Hamamatsu University School of Medicine  Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Baba","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology Hamamatsu University School of Medicine Hospital  Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6157-636X","authenticated-orcid":false,"given":"Hiroshi","family":"Inagaki","sequence":"additional","affiliation":[{"name":"Department of Pathology and Molecular Diagnostics Nagoya City University  Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chinatsu","family":"Tsuchiya","sequence":"additional","affiliation":[{"name":"Department of Pathology Shizuoka General Hospital  Shizuoka 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