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We present a case of carcinosarcoma with a well\u2010differentiated carcinomatous component that required a differential diagnosis from tumors derived from teratomas, such as teratocarcinosarcoma. We present a case of a 68\u2010year\u2010old man who visited our hospital for an examination of a 22\u2010mm lung tumor. The patient underwent left S1+2 segmentectomy, and his postoperative course was uneventful. No recurrence was observed in the 21\u2010month postoperative follow\u2010up period. The segmentectomy specimen revealed a yellow\u2010white, well\u2010circumscribed mass. The tumor consisted of well\u2010differentiated squamous and glandular epithelia, and sarcomatous components of immature spindle cells, chondrosarcoma, and rhabdomyosarcoma. The patient was diagnosed with carcinosarcoma. This case included well\u2010differentiated carcinomatous components, and it was necessary to differentiate it from teratocarcinosarcomas. There was no neural component, and without SMARCA4 loss, which is observed in teratocarcinosarcoma, and ruled out teratocarcinosarcoma. Carcinosarcomas are characterized by a biphasic histopathological pattern, making it difficult to accurately diagnose them on biopsy, which only captures a portion of the tumor. The possibility of carcinosarcoma should be considered even when the tumors derived from teratomas are suspected on preoperative biopsy.<\/jats:p>","DOI":"10.1111\/pin.70006","type":"journal-article","created":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T06:17:26Z","timestamp":1743315446000},"page":"196-202","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pulmonary Carcinosarcoma Imitating Teratocarcinosarcoma: A Case Report"],"prefix":"10.1111","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0311-5116","authenticated-orcid":false,"given":"Naoko","family":"Shigeta","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery Kanagawa Cancer Center Yokohama Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyuki","family":"Yokose","sequence":"additional","affiliation":[{"name":"Department of Pathology Kanagawa Cancer Center Yokohama Kanagawa 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