{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T16:49:23Z","timestamp":1765039763373,"version":"3.41.0"},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pathology International"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>We present a case of pancreatic ductal carcinoma with a microcystic appearance. A 64\u2010year\u2010old woman was found to have a pancreatic mass during a routine medical checkup. The tumor was well\u2010circumscribed and multicystic; thus, she was followed up for suspected serous cystadenoma. However, the tumor gradually enlarged in the following 2.5 years; subsequently, she underwent a Whipple procedure. Grossly, the cut surface of the tumor was honeycomb\u2010like with small cysts. Histologically, the cysts were ductal structures lined by a relatively bland, cuboidal or columnar epithelium with mildly enlarged nuclei. No intracytoplasmic mucus was observed. The presence of stromal invasion confirmed the diagnosis of ductal carcinoma. <jats:italic>KRAS<\/jats:italic> was wild type. Postoperative course was uneventful, with no recurrence to date (followup period: 5.5 years postsurgery). The present case did not meet any known subtypes of pancreatic ductal carcinoma. The tumor resembled a large duct variant, which typically shows a microcystic appearance. However, unlike the present case, the large duct type usually consists of mucus\u2010rich neoplastic cells. A recent study on cholangiocarcinoma proposed a novel tubulocystic subtype characterized by microcystic neoplastic glands and adenofibromatous stroma, which is morphologically similar to the present case. The present case may correspond to a pancreatic counterpart of tubulocystic cholangiocarcinoma.<\/jats:p>","DOI":"10.1111\/pin.70008","type":"journal-article","created":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T12:35:26Z","timestamp":1744893326000},"page":"243-246","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Potential Case of Tubulocystic Ductal Carcinoma of the Pancreas"],"prefix":"10.1111","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6956-8580","authenticated-orcid":false,"given":"Rena","family":"Uno","sequence":"first","affiliation":[{"name":"Department of Diagnostic Pathology, Hyogo Cancer Center Kita Oji\u2010cho Akashi City Hyogo Prefecture Japan"},{"name":"Department of Diagnostic Pathology Kobe University Hospital Kobe City Hyogo Prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8370-6508","authenticated-orcid":false,"given":"Yoh","family":"Zen","sequence":"additional","affiliation":[{"name":"Institute of Liver Studies, King's College Hospital London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomonori","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology Kobe University Hospital Kobe City Hyogo Prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirochika","family":"Toyama","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Hepato\u2010Biliary\u2010Pancreatic Surgery Kobe University Hospital, Chuo\u2010ku Kobe City Hyogo Prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takumi","family":"Fukumoto","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Hepato\u2010Biliary\u2010Pancreatic Surgery Kobe University Hospital, Chuo\u2010ku Kobe City Hyogo Prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keitaro","family":"Sofue","sequence":"additional","affiliation":[{"name":"Department of Radiology Kobe University Graduate School of Medicine, Chuo\u2010ku Kobe City Hyogo Prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoo","family":"Itoh","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology Kobe University Hospital Kobe City Hyogo Prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,17]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"Cancer Statistics in Japan [Homepage on the Internet (Cited January 19 2025) https:\/\/ganjoho.jp\/public\/qa_links\/report\/statistics\/2024_jp.html."},{"volume-title":"WHO Classification of Tumours Editorial Board, WHO Classification of Tumours Series, Digestive System Tumours","year":"2019","key":"e_1_2_12_3_1"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2011.181"},{"key":"e_1_2_12_5_1","article-title":"A Unicorn Disease: The Large Duct Variant of Invasive Ductal Adenocarcinoma of the Pancreas","volume":"15","author":"Elhariri A.","year":"2023","journal-title":"Cureus"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-004-0984-6"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radcr.2022.06.047"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318249ce1c"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3800446"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000002278"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2022.06.001"}],"container-title":["Pathology 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