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What's unique is that Langerhans cell histiocytosis (LCH) were identified in the LECs by immunohistochemistry (IHC) and molecular test. The inconspicuous LCH cells distributed along and mimicked the epithelial lining of cyst walls and were possibly to be missed in diagnosis. To date, there has no documented report of primary LCH originating within LECs. This study presents for the first time of a unique growth pattern. 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