{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T06:01:02Z","timestamp":1790748062249,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":28,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pathology International"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>We herein review the pathological diagnosis of nodal T follicular helper (TFH) cell lymphoma, angioimmunoblastic type (nTFHL\u2010AI), a mature T\u2010cell neoplasm with a TFH phenotype that was previously designated as angioimmunoblastic T\u2010cell lymphoma (AITL). The history of AITL from its discovery to the WHO 5th classification, which includes Japanese pathologists' and hematologists' contributions, is discussed. We then focus on what true neoplastic T cells of nTFHL\u2010Al are in histopathology. Since the number of neoplastic cells is small in some cases of nTFHL\u2010AI, the findings of recent single\u2010cell analyses to immunohistochemistry of TFH markers are considered. We also discuss Epstein\u2013Barr virus large B\u2010cells in AITL, particularly diffuse large B\u2010cell lymphoma and classic Hodgkin lymphoma (CHL), and propose how to make a differential diagnosis between nTFHL\u2010Al and CHL.<\/jats:p>","DOI":"10.1111\/pin.70186","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:45:16Z","timestamp":1790747116000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pathological Diagnosis of Nodal T Follicular Helper Cell Lymphoma, Angioimmunoblastic Type"],"prefix":"10.1111","volume":"76","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4332-5254","authenticated-orcid":false,"given":"Naoya","family":"Nakamura","sequence":"first","affiliation":[{"name":"Department of Pathology Tokai University School of Medicine Isehara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4982-8674","authenticated-orcid":false,"given":"Yara Yukie","family":"Kikuti","sequence":"additional","affiliation":[{"name":"Department of Pathology Tokai University School of Medicine Isehara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6129-8299","authenticated-orcid":false,"given":"Joaquim","family":"Carreras","sequence":"additional","affiliation":[{"name":"Department of Pathology Tokai University School of Medicine Isehara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8887-1593","authenticated-orcid":false,"given":"Ryota","family":"Matsuoka","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Institute of Medicine University of Tsukuba Tsukuba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Matsubara","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Institute of Medicine University of Tsukuba Tsukuba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2491-3798","authenticated-orcid":false,"given":"Sakurako","family":"Suma","sequence":"additional","affiliation":[{"name":"Department of Hematology, Institute of Medicine University of Tsukuba Tsukuba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamiko","family":"Sakata\u2010Yanagimoto","sequence":"additional","affiliation":[{"name":"Department of Hematology, Institute of Medicine University of Tsukuba Tsukuba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohei","family":"Masugi","sequence":"additional","affiliation":[{"name":"Department of Pathology Tokai University School of Medicine Isehara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"e_1_2_11_2_1","first-page":"744","volume-title":"Nodal T follicular helper cell lymphoma, angioimmunoblastic type. 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