{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T11:56:32Z","timestamp":1774958192990,"version":"3.50.1"},"reference-count":89,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,3,7]],"date-time":"2021-03-07T00:00:00Z","timestamp":1615075200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Plant Biol J"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n<jats:list list-type=\"bullet\">\n\n<jats:list-item><jats:p>A supply of plant micronutrients (some of which are metals) is necessary to regulate many plant processes; their excess, however, can have detrimental consequences and can hamper plant growth, physiology and metabolism.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p><jats:italic>Artemisia annua<\/jats:italic> is an important crop plant used in the treatment of malaria. In this investigation, the physio\u2010biochemical mechanisms involved in exogenous hydrogen sulphide\u2010mediated (H<jats:sub>2<\/jats:sub>S) alleviation of copper (Cu) stress in <jats:italic>A. annua<\/jats:italic> were assessed..<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>Two different levels of Cu (20, 40\u2009mg\u00b7kg<jats:sup>\u22121<\/jats:sup>), one H<jats:sub>2<\/jats:sub>S treatment (200\u2009\u00b5<jats:sc>m<\/jats:sc>) and their combinations were introduced while one set of plants was retained as control.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>Results showed that the presence of excess Cu in the soil reduced growth and biomass, photosynthetic parameters, chlorophyll content and fluorescence, gas exchange parameters and induced antioxidant enzyme activity. Copper stress enhanced the production of thiobarbituric acid reactive substances (TBARS) and increased Cu content in both roots and shoots of affected plants. Exogenous application of H<jats:sub>2<\/jats:sub>S restored the physio\u2010biochemical characteristics of Cu\u2010treated <jats:italic>A. annua<\/jats:italic> plants by reducing lipid peroxidation and enhancing the activity of antioxidant enzymes in Cu\u2010stressed plants as compared with the controls.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>Hydrogen sulphide also reduced the Cu content in different plant parts, increased photosynthetic efficiency, trichome density, average area of trichomes and artemisinin content. Therefore, our results provide a comprehensive assessment of the defensive role of H<jats:sub>2<\/jats:sub>S in Cu\u2010stressed <jats:italic>A. annua<\/jats:italic>.<\/jats:p><\/jats:list-item>\n<\/jats:list>\n<\/jats:p>","DOI":"10.1111\/plb.13242","type":"journal-article","created":{"date-parts":[[2021,2,6]],"date-time":"2021-02-06T01:16:02Z","timestamp":1612574162000},"page":"642-651","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Exogenous hydrogen sulphide alleviates copper stress impacts in <i>Artemisia annua<\/i> L.: Growth, antioxidant metabolism, glandular trichome development and artemisinin biosynthesis"],"prefix":"10.1111","volume":"24","author":[{"given":"L.","family":"Nomani","sequence":"first","affiliation":[{"name":"Department of Botany Aligarh Muslim University  Aligarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Zehra","sequence":"additional","affiliation":[{"name":"Department of Botany Aligarh Muslim University  Aligarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Choudhary","sequence":"additional","affiliation":[{"name":"Department of Botany Aligarh Muslim University  Aligarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. 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