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While ascorbic acid (AA) and salicylic acid (SA) are recognized as protective agents against abiotic stress, their comparative efficacy and synergistic potential under combined stress remain poorly understood.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>\n                          This study evaluated individual and combined applications of AA (100\u2009mg\u00b7L\n                          <jats:sup>\u22121<\/jats:sup>\n                          , equivalent to 0.57\u2009mM) and SA (0.5\u2009mM) on maize (\u2018Zhengdan No. 16\u2019) subjected to four water regimes: well\u2010watered (WW 100%), mild water stress (MWS 75%), moderate water stress (MoWS, 50%), and severe water stress (SWS, 30% field capacity), with or without Pb (200\u2009\u03bcM) or Cd (100\u2009\u03bcM) exposure. Photosynthetic pigments, gas exchange, phytohormones (ABA, IAA), oxidative stress markers (H\n                          <jats:sub>2<\/jats:sub>\n                          O\n                          <jats:sub>2<\/jats:sub>\n                          , SOD), and macronutrient uptake (N, P, K) were quantified. The Pb concentration (200\u2009\u03bcM) was selected based on preliminary dose\u2013response experiments (0, 100, 200, 400\u2009\u03bcM), where 200\u2009\u03bcM caused significant but non\u2010lethal growth inhibition (30%\u201340% biomass reduction), allowing assessment of AA\/SA mitigation without complete growth arrest.\n                        <\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>\n                          Under WW conditions, AA increased chlorophyll a by 11.0% and SA by 14.5% versus controls. Combined AA+SA\u2009+\u2009Cd improved selected nutrient responses, including a 2.8% increase in leaf N and a 4.5% increase in leaf K relative to Cd alone under WW conditions; however, leaf P did not increase under all water regimes. AA reduced Cd\u2010triggered H\n                          <jats:sub>2<\/jats:sub>\n                          O\n                          <jats:sub>2<\/jats:sub>\n                          by approximately 30% and Pb\u2010triggered H\n                          <jats:sub>2<\/jats:sub>\n                          O\n                          <jats:sub>2<\/jats:sub>\n                          by approximately 18% (\n                          <jats:italic>P<\/jats:italic>\n                          \u2009&lt;\u20090.05). Under SWS, combined treatments improved selected photoprotective responses, including a 14.3% increase in carotenoid content, although Chl a responses were treatment and metal\u2010specific.\n                        <\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Exogenous AA and SA, particularly in combination, enhance dryland maize resilience to combined drought and HM stress through improved photosynthesis, reduced oxidative damage, and optimized nutrient acquisition. These findings support antioxidant biostimulants as sustainable tools for crop stress.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:p>","DOI":"10.1111\/plb.70250","type":"journal-article","created":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T11:32:33Z","timestamp":1782732753000},"page":"1973-1988","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effects of ascorbic acid and salicylic acid on drought resilience and mitigation of lead and cadmium toxicity in dryland maize (\n                    <i>Zea mays<\/i>\n                    L.)"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5856-3189","authenticated-orcid":false,"given":"F.","family":"Ullah","sequence":"first","affiliation":[{"name":"College of Life Sciences, Northwest Normal University  Lanzhou 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