{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T09:14:39Z","timestamp":1791105279364,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,10,10]],"date-time":"2013-10-10T00:00:00Z","timestamp":1381363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Our objectives were to examine the associations of neonatal and infant mortality with preterm birth and intrauterine growth restriction (<jats:styled-content style=\"fixed-case\">IUGR<\/jats:styled-content>), and to estimate the partial population attributable risk per cent (<jats:styled-content style=\"fixed-case\">pPAR<\/jats:styled-content>%) of neonatal and infant mortality due to preterm birth and <jats:styled-content style=\"fixed-case\">IUGR<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants were <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010negative pregnant women and their infants enrolled in <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ar es <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>alaam, <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>anzania. Gestational age calculated from date of last menstrual period was used to define preterm, and small for gestational age (<jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>) was used as proxy for <jats:styled-content style=\"fixed-case\">IUGR<\/jats:styled-content>. Survival of infants was ascertained at monthly follow\u2010up visits. Cox proportional hazard models were used to estimate the associations of preterm and <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> with neonatal and infant mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Study included 7225 singletons, of whom 15% were preterm and 21% were <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content>; majority of preterm or <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> babies had birthweight \u22652500\u2009g. Compared to term and appropriately sized babies (<jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content>), relative risks (<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content>) of neonatal mortality among preterm\u2010<jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content> was 2.6 [95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.8, 3.9], <jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content> among term\u2010<jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> was 2.3 [95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.6, 3.3], and the highest risk was among the preterm\u2010<jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> babies (<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content> 15.1 [95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 8.2, 27.7]). Risk associated with preterm was elevated throughout the infancy, and risk associated with <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> was elevated during the neonatal period only. The <jats:styled-content style=\"fixed-case\">pPAR<\/jats:styled-content>% of neonatal mortality for preterm was 22% [95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 17%, 26%] and for <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> it was 26% [95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 16%, 36%].<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Preterm and <jats:styled-content style=\"fixed-case\">SGA<\/jats:styled-content> birth substantially increased the risk of mortality. Interventions for prevention and management of these conditions are likely to reduce of infant mortality in <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>anzania.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ppe.12085","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T02:42:38Z","timestamp":1381545758000},"page":"23-31","source":"Crossref","is-referenced-by-count":29,"title":["The Contribution of Preterm Birth and Intrauterine Growth Restriction to Infant Mortality in <scp>T<\/scp>anzania"],"prefix":"10.1111","volume":"28","author":[{"given":"Ayesha","family":"Sania","sequence":"first","affiliation":[{"name":"Department of Epidemiology Harvard School of Public Health  Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donna","family":"Spiegelman","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard School of Public Health  Boston MA"},{"name":"Department of Biostatistics Harvard 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