{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T07:07:07Z","timestamp":1780988827619,"version":"3.54.1"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,10,10]],"date-time":"2013-10-10T00:00:00Z","timestamp":1381363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To investigate the risk for subsequent cardiovascular events in women having placental abruption during a follow\u2010up period of more than 10 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A population\u2010based study of the incidence of cardiovascular events in women who had placental abruption with women without placental abruption during 1988\u201399 and with follow\u2010up until 2010. Associations between placental abruption and maternal long\u2010term cardiovascular morbidity and mortality were investigated. Kaplan\u2013Meier survival curves and multivariable Cox regression were used to estimate cumulative incidence of cardiovascular mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the study period, there were 47\u2009585 deliveries meeting the inclusion criteria; of these, 653 occurred in patients with placental abruption. No significant association was noted between placental abruption and subsequent long\u2010term hospitalisations because of cardiovascular causes. However, placental abruption was associated with long\u2010term cardiovascular mortality [odds ratio (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>)\u2009=\u20096.6; 95% confidence interval (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>) 2.3, 18.3]. The cardiovascular case fatality rate for the placental abruption group was 13.0% vs. 2.5% in the comparison group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Patients with a history of placental abruption had a significantly higher risk for cardiovascular mortality during the follow\u2010up period (Log\u2010rank test <jats:italic>P<\/jats:italic>\u2009=\u20090.017). Using Cox multivariable regression models, placental abruption remained an independent risk factor for long\u2010term maternal cardiovascular mortality [adjusted hazard ratio (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>)\u2009=\u20094.3; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.1, 18.6).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Placental abruption is a significant risk factor for long\u2010term cardiovascular mortality in a follow\u2010up period of more than a decade.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ppe.12089","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T02:37:28Z","timestamp":1381545448000},"page":"32-38","source":"Crossref","is-referenced-by-count":45,"title":["Placental Abruption as a Significant Risk Factor for Long\u2010term Cardiovascular Mortality in a Follow\u2010up Period of More Than a Decade"],"prefix":"10.1111","volume":"28","author":[{"given":"Gali","family":"Pariente","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Soroka University Medical Center, Faculty of Health Sciences Ben\u2010Gurion University of the Negev  Beer\u2010Sheva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilana","family":"Shoham\u2010Vardi","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Health Services Evaluation Ben\u2010Gurion University of the Negev  Beer\u2010Sheva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy","family":"Kessous","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Soroka University Medical Center, Faculty of Health Sciences Ben\u2010Gurion University of the Negev  Beer\u2010Sheva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Sherf","sequence":"additional","affiliation":[{"name":"Soroka University Medical Center Clalit Health Services (Southern District) Faculty of Health Sciences Ben\u2010Gurion University of the Negev  Beer\u2010Sheva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eyal","family":"Sheiner","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Soroka University Medical Center, Faculty of Health Sciences Ben\u2010Gurion University of the Negev  Beer\u2010Sheva Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,10]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/jmf.11.1.34.39"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(96)00088-9"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1997.tb11535.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2010.511346"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/jmf.13.1.45.49"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1016248"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.12.1607"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.EDE.0000059921.71494.D1"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200106000-00008"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2004.01.038"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2006.01858.x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)05112-6"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.323.7323.1213"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.326.7394.845"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwh064"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ede.0000152912.02042.cd"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.109.130765"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67726-4"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2010.01120.x"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200109000-00037"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000425667.10377.60"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2004.00557.x"},{"key":"e_1_2_5_24_1","first-page":"67","article-title":"Diagnosis and management of preeclampsia and eclampsia. 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