{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T07:30:33Z","timestamp":1780731033146,"version":"3.54.1"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,2,10]],"date-time":"2014-02-10T00:00:00Z","timestamp":1391990400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["NO1-ES-75558"],"award-info":[{"award-number":["NO1-ES-75558"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["UO1 NS 047537-01"],"award-info":[{"award-number":["UO1 NS 047537-01"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["UO1 NS047537-06A1"],"award-info":[{"award-number":["UO1 NS047537-06A1"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Maternal folic acid supplementation between subsequent pregnancies may be important to reduce the risk of low folate status associated with short interpregnancy intervals. We examined how the prevalence of preconception folic acid use for a given pregnancy in <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>orwegian women varied according to the time interval from the previous pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Analysis was based on 48\u2009855 pairs of pregnancies with the second pregnancy included in the <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>orwegian <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>other and <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hild <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ohort <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tudy (birth years 1999\u20132009). Interpregnancy interval was defined as the time from birth of a child to the conception of the subsequent sibling. Preconception folic acid use was defined as any use of folic acid\u2010containing supplements within the last 4 weeks before the second pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of preconception folic acid use was 31%. Among women with a term birth (\u226537 weeks) in the previous pregnancy (92%), those with interpregnancy intervals \u226412 and \u226549 months were associated with up to 35% lower prevalence of preconception folic acid use for the second pregnancy, relative to the reference group (13\u201324 months). The low use in short intervals was mainly attributable to lower proportion of planned pregnancies and fewer women with higher education. Among women with a preterm birth (&lt;37 weeks) in the previous pregnancy (8%), preconception folic acid use significantly decreased with increasing pregnancy spacing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our finding of a lower preconception folic acid use in women with both short and long interpregnancy intervals might help identifying those with higher risk of folate deficiency and preventing unwanted pregnancy outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ppe.12111","type":"journal-article","created":{"date-parts":[[2014,2,10]],"date-time":"2014-02-10T06:16:42Z","timestamp":1392013002000},"page":"270-274","source":"Crossref","is-referenced-by-count":20,"title":["Folic Acid Supplementation and Interpregnancy Interval"],"prefix":"10.1111","volume":"28","author":[{"given":"Roy Miodini","family":"Nilsen","sequence":"first","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen  Bergen Norway"},{"name":"Alessandra Lisi International Centre on Birth Defects and Prematurity  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierpaolo","family":"Mastroiacovo","sequence":"additional","affiliation":[{"name":"Alessandra Lisi International Centre on Birth Defects and Prematurity  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Gunnes","sequence":"additional","affiliation":[{"name":"Norwegian Institute of Public Health  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elin R.","family":"Alsaker","sequence":"additional","affiliation":[{"name":"Norwegian Institute of Public Health  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Lise","family":"Bj\u00f8rke\u2010Monsen","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical Biochemistry Haukeland University Hospital  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone J. P. M.","family":"Eussen","sequence":"additional","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen  Bergen Norway"},{"name":"Section for Pharmacology Institute of Medicine University of Bergen  Bergen Norway"},{"name":"Department of Epidemiology School for Public Health and Primary Care \u2013 CAPHRI Maastricht University  Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaretha","family":"Haugen","sequence":"additional","affiliation":[{"name":"Norwegian Institute of Public Health  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ane","family":"Johannessen","sequence":"additional","affiliation":[{"name":"Centre for Clinical Research Haukeland University Hospital  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helle Margrete","family":"Meltzer","sequence":"additional","affiliation":[{"name":"Norwegian Institute of Public Health  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla","family":"Stoltenberg","sequence":"additional","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen  Bergen Norway"},{"name":"Norwegian Institute of Public Health  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per Magne","family":"Ueland","sequence":"additional","affiliation":[{"name":"Section for Pharmacology Institute of Medicine University of Bergen  Bergen Norway"},{"name":"Laboratory of Clinical Biochemistry Haukeland University Hospital  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stein Emil","family":"Vollset","sequence":"additional","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen  Bergen Norway"},{"name":"Norwegian Institute of Public Health  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,2,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68582-6"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38336.664352.82"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199911113412001"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199212243272602"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)90133-A"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2008.06.014"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/84.5.1134"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/09674845.2004.11732649"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1079\/BJN2001376"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)07105-7"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/88.1.147"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/133.5.1732S"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyl170"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2009.01062.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/ppe.12077"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ede.0000434435.52506.f5"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/71.5.1295s"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2005.00606.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2011.49"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.111.092916"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2004.00115.x"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/14034940310019515"}],"container-title":["Paediatric and Perinatal Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fppe.12111","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ppe.12111","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T20:06:30Z","timestamp":1696190790000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ppe.12111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,10]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["10.1111\/ppe.12111"],"URL":"https:\/\/doi.org\/10.1111\/ppe.12111","archive":["Portico"],"relation":{},"ISSN":["0269-5022","1365-3016"],"issn-type":[{"value":"0269-5022","type":"print"},{"value":"1365-3016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,10]]}}}