{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T16:17:09Z","timestamp":1770740229968,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,5,28]],"date-time":"2014-05-28T00:00:00Z","timestamp":1401235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Preterm delivery is a major cause of neonatal morbidity and mortality. Human papillomavirus (<jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content>) infection is common in reproductive\u2010aged women. We hypothesised that abnormal cervical cancer screening tests, as a proxy for <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> infection, would be associated with preterm delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective cohort study of women delivering liveborn singletons beyond 20 weeks gestation, who had a <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>apanicolaou (<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>ap) test within 1 year prior to delivery. Women with abnormal <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>ap or positive high\u2010risk <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> tests, classified as having \u2018abnormal screening\u2019, were compared with women classified as having \u2018normal screening\u2019 in bivariate analysis for overall preterm delivery at less than 37 weeks gestation. Using <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>oisson regression, we report unadjusted (RR) and adjusted (aRR) risk ratios for spontaneous preterm delivery due to preterm labour and preterm premature rupture of membranes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 2686 women meeting criteria for analysis, 213 (8%) had abnormal screening. Women with abnormal screening, compared with normal screening, were not more likely to deliver preterm (12.2% vs. 9.8%, <jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content> 1.3 [95% confidence interval (CI) 0.9, 1.8], <jats:styled-content style=\"fixed-case\">aRR<\/jats:styled-content> 1.2 [95% CI 0.8, 1.7]). Women with abnormal screening, however, were at greater risk for spontaneous preterm delivery in unadjusted and adjusted analysis (8.9% vs. 4.5%; <jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content> 2.0 [95% CI 1.2, 3.2], aRR 1.8 [95% CI 1.1, 2.9]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There was no difference in risk of overall preterm delivery in women with abnormal compared with normal cervical cancer screening tests. Our data suggest, however, that abnormal screening in pregnancy may be associated with spontaneous preterm delivery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ppe.12132","type":"journal-article","created":{"date-parts":[[2014,5,29]],"date-time":"2014-05-29T00:26:52Z","timestamp":1401323212000},"page":"297-301","source":"Crossref","is-referenced-by-count":17,"title":["Abnormal Cervical Cancer Screening in Pregnancy and Preterm Delivery"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1205-3789","authenticated-orcid":false,"given":"Jennifer N.","family":"Hong","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Hawaii  Honolulu HI"},{"name":"Department of Obstetrics and Gynecology John A. Burns School of Medicine University of Hawaii  Honolulu HI"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erica K.","family":"Berggren","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Hawaii  Honolulu HI"},{"name":"Department of Obstetrics and Gynecology Thomas Jefferson University  Philadelphia PA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara L.","family":"Campbell","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Hawaii  Honolulu HI"},{"name":"Department of Obstetrics and Gynecology Thomas Jefferson University  Philadelphia PA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer S.","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Epidemiology The University of North Carolina at Chapel Hill  Chapel Hill NC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Rahangdale","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Hawaii  Honolulu HI"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,5,28]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767050600965882"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2006.05.001"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-199707000-00008"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2009.02237.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767050802360783"},{"issue":"11","key":"e_1_2_5_7_1","first-page":"1","article-title":"Sexually transmitted diseases treatment guidelines, 2006","volume":"55","author":"Workowski 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