{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:43:38Z","timestamp":1788871418461,"version":"build-2803163510"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,9,16]],"date-time":"2014-09-16T00:00:00Z","timestamp":1410825600000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R21-050264"],"award-info":[{"award-number":["R21-050264"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["T32HD052458"],"award-info":[{"award-number":["T32HD052458"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2014,9]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n Several studies indicate that female obesity increases the risk of spontaneous abortion (\n SAB<\/jats:styled-content>\n ). Central adiposity, height, and location of typical weight gain have not been examined as risk factors for\n SAB<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n We examined the associations between selected anthropometric factors and risk of\n SAB<\/jats:styled-content>\n among 5132 women enrolled in a\n D<\/jats:styled-content>\n anish\n I<\/jats:styled-content>\n nternet\u2010based prospective cohort study of pregnancy planners. We used\n C<\/jats:styled-content>\n ox proportional hazards regression models, with gestational weeks as the time scale, to compute hazard ratios (\n HR<\/jats:styled-content>\n s) of\n SAB<\/jats:styled-content>\n and 95% confidence intervals (\n CI<\/jats:styled-content>\n s).\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n After adjustment for potential confounders, the\n HR<\/jats:styled-content>\n s for\n SAB<\/jats:styled-content>\n among underweight (body mass index (\n BMI<\/jats:styled-content>\n , kg\/m\n 2<\/jats:sup>\n ) <20), overweight (\n BMI<\/jats:styled-content>\n : 25\u201329) and obese (\n BMI<\/jats:styled-content>\n \u226530) women were 1.00 [95%\n CI<\/jats:styled-content>\n : 0.81, 1.24], 0.90 [95%\n CI<\/jats:styled-content>\n : 0.73, 1.09] and 1.23 [95%\n CI<\/jats:styled-content>\n : 0.98, 1.54], respectively, compared with normal weight women (\n BMI<\/jats:styled-content>\n 20\u201324). The association between obesity and\n SAB<\/jats:styled-content>\n was stronger for early\n SAB<\/jats:styled-content>\n (<8 weeks gestation);\n HR<\/jats:styled-content>\n : 1.34 95%\n CI<\/jats:styled-content>\n : 1.01, 1.77. The\n HR<\/jats:styled-content>\n for height \u2265174\u2009cm vs. <166\u2009cm was 0.81 [95%\n CI<\/jats:styled-content>\n : 0.66, 1.00]. Increased waist\u2010to\u2010hip ratio (\n WHR<\/jats:styled-content>\n ) was inversely associated with risk of\n SAB<\/jats:styled-content>\n (\n HR<\/jats:styled-content>\n : 0.81; 95%\n CI<\/jats:styled-content>\n : 0.63, 1.05). Waist circumference and location of typical weight gain were not appreciably associated with\n SAB<\/jats:styled-content>\n risk.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n This study confirms previous studies that have shown a small positive association between obesity and\n SAB<\/jats:styled-content>\n risk. Our results suggest that obesity is a stronger risk factor for early pregnancy losses, and that small stature and low\n WHR<\/jats:styled-content>\n are associated with an increased risk of\n SAB<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ppe.12142","type":"journal-article","created":{"date-parts":[[2014,9,16]],"date-time":"2014-09-16T02:57:10Z","timestamp":1410836230000},"page":"412-423","source":"Crossref","is-referenced-by-count":49,"title":["Body Size and Risk of Spontaneous Abortion among Danish Pregnancy Planners"],"prefix":"10.1111","volume":"28","author":[{"given":"Kristen A.","family":"Hahn","sequence":"first","affiliation":[{"name":"Department of Epidemiology Boston University School of Public Health Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth E.","family":"Hatch","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Boston University School of Public Health Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth J.","family":"Rothman","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Boston University School of Public Health Boston MA"},{"name":"RTI Health Solutions Research Triangle Park NC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen M.","family":"Mikkelsen","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan B.","family":"Brogly","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Boston University School of Public Health Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik T.","family":"S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Boston University School of Public Health Boston MA"},{"name":"Department of Clinical Epidemiology 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