{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T01:21:09Z","timestamp":1789348869662,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,10,30]],"date-time":"2014-10-30T00:00:00Z","timestamp":1414627200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"US Dept. og Health and Human Services","award":["ES044003-36"],"award-info":[{"award-number":["ES044003-36"]}]},{"name":"Western Norwegian Regional Health Authoority"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2014,11]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Maternal asthma has been associated with adverse pregnancy outcomes. Little is known about the influence of other atopic diseases on pregnancy outcomes. We assessed how various maternal atopic diseases might affect preterm birth, stillbirth, and neonatal death.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n By linking\n N<\/jats:styled-content>\n orwegian national registries, we acquired information on maternal health, socio\u2010demographic factors, pregnancy, birth, and neonatal outcome on all births in\n N<\/jats:styled-content>\n orway from 1967 to 2003.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 1\u2009974\u2009226 births were included. Of these, 1.8% had a record of maternal asthma, 3.4% of maternal atopic dermatitis, and 0.4% of maternal allergic rhinoconjunctivitis. Overall rates of preterm birth, stillbirth, and neonatal death were 6.0%, 0.6%, and 0.5%, respectively. After adjustments for possible confounders, maternal asthma was associated with increased risk of preterm birth (relative risk (\n RR<\/jats:styled-content>\n ), 1.15, [95% confidence interval (\n CI<\/jats:styled-content>\n ) 1.10, 1.21]). In contrast, maternal atopic dermatitis was associated with decreased risk of preterm birth (\n RR<\/jats:styled-content>\n 0.90, [95%\n CI<\/jats:styled-content>\n 0.86, 0.93]), stillbirth (\n RR<\/jats:styled-content>\n 0.70, [95%\n CI<\/jats:styled-content>\n 0.62, 0.79]), and neonatal death (\n RR<\/jats:styled-content>\n 0.76, [95%\n CI<\/jats:styled-content>\n 0.65, 0.90]). Similarly, maternal allergic rhinoconjunctivitis was associated with decreased risk of preterm birth (\n RR<\/jats:styled-content>\n 0.84, [95%\n CI<\/jats:styled-content>\n 0.76, 0.94]) and stillbirth (\n RR<\/jats:styled-content>\n 0.40, [95%\n CI<\/jats:styled-content>\n 0.25, 0.66]).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n We confirmed the previously reported association of maternal asthma with increased risk for preterm birth. Unexpectedly, maternal atopic dermatitis and allergic rhinoconjunctivitis were associated with decreased risk of preterm birth and stillbirth. Mechanisms for these protective associations are unclear, and our findings require confirmation in further studies.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ppe.12154","type":"journal-article","created":{"date-parts":[[2014,10,30]],"date-time":"2014-10-30T08:17:44Z","timestamp":1414657064000},"page":"489-497","source":"Crossref","is-referenced-by-count":28,"title":["Associations of Maternal Atopic Diseases with Adverse Pregnancy Outcomes: a National Cohort Study"],"prefix":"10.1111","volume":"28","author":[{"given":"H\u00e5vard","family":"Tr\u00f8nnes","sequence":"first","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen Bergen Norway"},{"name":"Department of Pediatrics Haukeland University Hospital Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allen J.","family":"Wilcox","sequence":"additional","affiliation":[{"name":"Epidemiology Branch National Institute of Environmental Health Sciences National Institutes of Health Durham NC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trond","family":"Markestad","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine University of Bergen Bergen Norway"},{"name":"Department of Pediatrics Haukeland University Hospital Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mette Christophersen","family":"Toll\u00e5nes","sequence":"additional","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolv Terje","family":"Lie","sequence":"additional","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen Bergen Norway"},{"name":"Medical Birth Registry of Norway Norwegian Institute of Public Health Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dag","family":"Moster","sequence":"additional","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen Bergen Norway"},{"name":"Department of Pediatrics Haukeland University Hospital Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,30]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2009.03366.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2011.03055.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12224"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-011-0178-7"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5699(93)90235-D"},{"key":"e_1_2_6_7_1","unstructured":"Norwegian Institute of Public Health.Medical Birth Registry of 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