{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T06:16:20Z","timestamp":1697177780186},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,9,14]],"date-time":"2015-09-14T00:00:00Z","timestamp":1442188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The association between folic acid (<jats:styled-content style=\"fixed-case\">FA<\/jats:styled-content>) insufficiency and congenital malformations has been demonstrated in over the past two decades. The aim of the present study was to investigate the use and timing of folate intake among a large sample of pregnant women in a north Italian region.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A multicentre prospective cohort study was conducted over a 14\u2010month period in the maternity wards of five general hospitals (2301 women). Data were collected via a face\u2010to\u2010face interview.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seven hundred sixty women (33%) took at least one product containing <jats:styled-content style=\"fixed-case\">FA<\/jats:styled-content>. Seven hundred thirty\u2010three (31.8%) women consumed multivitamins containing 413 (17.9%) consumed products containing <jats:styled-content style=\"fixed-case\">FA<\/jats:styled-content> only and 17 (0.7%) 15\u2009mg of levofolinic acid. Only 0.9% of all women took <jats:styled-content style=\"fixed-case\">FA<\/jats:styled-content> before pregnancy 72.5% of women who consumed <jats:styled-content style=\"fixed-case\">FA<\/jats:styled-content> started during the first trimester. The most common dosage was 0.4\u2009mg (19.4%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Very few women in the population are taking <jats:styled-content style=\"fixed-case\">FA<\/jats:styled-content> before pregnancy. Moreover, while most women consuming <jats:styled-content style=\"fixed-case\">FA<\/jats:styled-content> started in the first trimester, it is likely that they did so after closure of the neural tube. An important action is the recommendation that periconceptional supplementation programmes be promoted.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ppe.12226","type":"journal-article","created":{"date-parts":[[2015,9,14]],"date-time":"2015-09-14T12:53:22Z","timestamp":1442235202000},"page":"501-504","source":"Crossref","is-referenced-by-count":5,"title":["Poor Folate Intake in a North <scp>I<\/scp>talian Pregnant Population: an Epidemiological Survey"],"prefix":"10.1111","volume":"29","author":[{"given":"Giulia","family":"Dante","sequence":"first","affiliation":[{"name":"Mother\u2010Infant Department, Obstetric Unit University of Modena and Reggio Emilia  Modena Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Letizia","family":"Morani","sequence":"additional","affiliation":[{"name":"Mother\u2010Infant Department, Obstetric Unit University of Modena and Reggio Emilia  Modena Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisy","family":"Bronzetti","sequence":"additional","affiliation":[{"name":"Obstetric Unit Ospedale Infermi Rimini  Rimini Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Garutti","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Unit Azienda Ospedaliero\u2010Universitaria S.Anna  Ferrara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabella","family":"Neri","sequence":"additional","affiliation":[{"name":"Mother\u2010Infant Department, Obstetric Unit University of Modena and Reggio Emilia  Modena Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gioacchino","family":"Calapai","sequence":"additional","affiliation":[{"name":"School and Division of Allergology and Clinical Immunology University of Messina  Messina Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Facchinetti","sequence":"additional","affiliation":[{"name":"Mother\u2010Infant Department, Obstetric Unit University of Modena and Reggio Emilia  Modena Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,9,14]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2001.00162.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2013.11.008"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.23166"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2012.01276.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2005.00633.x"},{"key":"e_1_2_5_7_1","unstructured":"Euro\u2010Peristat Project.European perinatal health report. 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