{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:44:28Z","timestamp":1790127868005,"version":"4.0.1"},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,1,6]],"date-time":"2016-01-06T00:00:00Z","timestamp":1452038400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Health Care and Promotion Fund, Government of the Hong Kong SAR","award":["216106"],"award-info":[{"award-number":["216106"]}]},{"name":"Health and Health Services Research Fund, Government of the Hong Kong SAR","award":["03040771"],"award-info":[{"award-number":["03040771"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Preterm birth, early term birth, and low birthweight are associated with childhood wheezing disorders in developed Western settings, but observed associations could be confounded by socio\u2010economic position. This study aims to clarify such associations in a developed non\u2010<jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>estern setting with a different confounding structure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using Cox regression, we examined the adjusted associations of gestational age and birthweight for gestational age with time to first public hospital admission for asthma, bronchitis, and bronchiolitis (<jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>nternational <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>lassification of <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>iseases, <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>inth <jats:styled-content style=\"fixed-case\">V<\/jats:styled-content>ersion <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>linical <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>odification 466, 490, and 493) from 9 days to 12 years in a population\u2010representative birth cohort of 8327 <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hinese children in <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ong <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>ong, a developed setting with less clear social patterning of prematurity or birthweight. Analyses were adjusted for infant and parental characteristics and socio\u2010economic position.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Children born late preterm (34 to &lt;37 weeks) had higher risk of hospitalisation for asthma and other wheezing disorders [hazard ratio (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>) 1.99, 95% confidence interval (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>) 1.48, 2.67] than children born full term (39 to &lt;41 weeks). Early term births (37 to &lt;39 weeks) had <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> 1.01 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.84, 1.22), late term births (41 to &lt;42 weeks) had <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> 0.77 (95% 0.59, 1.01), and post\u2010term births (\u226542 weeks) had <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> 0.56 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.32, 0.98). Large for gestational age was associated with lower risk of hospitalisation (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> 0.76, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.57, 0.99).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The association of preterm birth with childhood wheezing could be biologically mediated. We cannot rule out an association for early term births.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ppe.12273","type":"journal-article","created":{"date-parts":[[2016,1,7]],"date-time":"2016-01-07T12:22:38Z","timestamp":1452169358000},"page":"149-159","source":"Crossref","is-referenced-by-count":25,"title":["Gestational Age, Birthweight for Gestational Age, and Childhood Hospitalisations for Asthma and Other Wheezing Disorders"],"prefix":"10.1111","volume":"30","author":[{"given":"June Y. Y.","family":"Leung","sequence":"first","affiliation":[{"name":"School of Public Health Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9912-0544","authenticated-orcid":false,"given":"Hugh S.","family":"Lam","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Faculty of Medicine The Chinese University of Hong Kong  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel M.","family":"Leung","sequence":"additional","affiliation":[{"name":"School of Public Health Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Mary","family":"Schooling","sequence":"additional","affiliation":[{"name":"School of Public Health Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong China"},{"name":"School of Public Health and Hunter College City University of New York  New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,1,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2009.02244.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2012-203079"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.12.1082"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001596"},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","unstructured":"ACOG Committee Opinion No 579: definition of term pregnancy. 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