{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:19:44Z","timestamp":1787015984700,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,8,8]],"date-time":"2016-08-08T00:00:00Z","timestamp":1470614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Bradford city has high infant mortality and there is a major health concern in the community due to environmental pollution. The aim of the study was to investigate the incidence and burden of wheezing disorders, eczema, and rhinitis in children aged 3\u20137 years .<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>It is a prospective cohort study; the participants were 13 734 children from the Born in Bradford cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were a total of 22.1% (95% Confidence Interval (\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      ) 21.4, 22.8%), 52.4% (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      51.5%, 53.2%), and 19.3% (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      18.6, 19.9%) incidence cases of wheezing disorders, eczema, and rhinitis respectively. A total of 37% (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      36.2%, 37.8%), 19.5% (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      18.9%, 20.2%,) and 5.9% (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      5.5%, 6.3%) of the children were affected by only one, two, and three diseases respectively. Boys to girls incidence rate ratios for wheezing disorders, eczema, and rhinitis was 1.41 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      1.31, 1.51), 1.02 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      0.97, 1.07), and 1.18 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      1.09, 1.28) respectively. The respective incidence rate ratios of Pakistani to White British were 0.94 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      0.87, 1.02), 1.31 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      1.24, 1.39), and 2.03 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      1.83, 2.25) respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study shows that the burden of wheezing disorders, eczema, and rhinitis in this cohort is higher than previously reported in earlier studies. In addition, it indicates that while boys are more likely to suffer from wheezing disorders, rhinitis, and multiple diseases than girls, Pakistani children are more likely to suffer from eczema, rhinitis, and multiple diseases than White British children.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ppe.12310","type":"journal-article","created":{"date-parts":[[2016,8,8]],"date-time":"2016-08-08T14:30:43Z","timestamp":1470666643000},"page":"594-602","source":"Crossref","is-referenced-by-count":10,"title":["Incidence and Burden of Wheezing Disorders, Eczema, and Rhinitis in Children: findings from the Born in Bradford Cohort"],"prefix":"10.1111","volume":"30","author":[{"given":"Teumzghi F.","family":"Mebrahtu","sequence":"first","affiliation":[{"name":"Centre for Reviews and Dissemination University of York York UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard G.","family":"Feltbower","sequence":"additional","affiliation":[{"name":"Division of Epidemiology and Biostatistics School of Medicine University of Leeds Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger C.","family":"Parslow","sequence":"additional","affiliation":[{"name":"Division of Epidemiology and Biostatistics School of Medicine University of Leeds Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69283-0"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2006.070169"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2004.00526.x"},{"key":"e_1_2_6_5_1","unstructured":"Eczema\u2010UK.The National Eczema Society: What is Eczema? 2015; [online] available:http:\/\/www.eczema.org\/what-is-eczema[accessed February 02 2015]."},{"key":"e_1_2_6_6_1","unstructured":"Asthma\u2010UK.Asthma Facts.2014; [online] available:http:\/\/www.asthma.org.uk\/asthma-facts-and-statistics. [accessed February 02 2015]."},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-8-327"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dys112"},{"key":"e_1_2_6_9_1","unstructured":"Bradford District Infant Mortality Commission (BDIMC).Bradford District Infant Mortality Commission Report 2006.2007; [online] available:http:\/\/www.observatory.bradford.nhs.uk\/SiteCollectionDocuments\/Infant%20Mortality%20Report%202006.pdf[accessed May 20 2015]."},{"key":"e_1_2_6_10_1","unstructured":"Bradford District Infant Mortality Commission (BDIMC).Bradford Joint Strategic Needs Assessment: Infant mortality in Bradford district.2014; [online] available:http:\/\/www.observatory.bradford.nhs.uk\/Documents\/4_5_1_Infant_Mortality_2014.pdf[accessed May 22 2015]."},{"key":"e_1_2_6_11_1","unstructured":"TPP.SystmOne. [online] available:https:\/\/www.tpp-uk.com\/products\/systmone[accessed June 27 2016]."},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)70195-1"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/02770900802513023"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2009.03248.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)04248-7"},{"key":"e_1_2_6_16_1","unstructured":"Global Initiative for Asthma (GINA).Global Strategy for Asthma Management and Prevention 2014. Chapter 6: Diagnosis and management of asthma in children 5 years and younger 2015. [online] available:http:\/\/ginasthma.org\/wp-content\/uploads\/2016\/01\/GINA_Report_2015_Aug11-1.pdf[accessed June 27 2016]."},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102015\u2010009553"},{"key":"e_1_2_6_18_1","unstructured":"BoodhnaG HallJ.Health Survey for England 2010: Respiratory Symptoms and Asthma in children.2011; [online] available:http:\/\/www.hscic.gov.uk\/catalogue\/PUB03023\/heal-surv-eng-2010-resp-heal-ch4-symp-chil.pdf[accessed March 10 2015]."},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3038.13.s.15.3.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dys064"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.46692\/9781847421418"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0111922"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001748"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2008.140681"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1258\/jrsm.2009.080211"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1258\/jrsm.2008.080096"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.3132\/pcrj.2007.00006"}],"container-title":["Paediatric and Perinatal Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fppe.12310","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fppe.12310","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ppe.12310","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T12:32:17Z","timestamp":1696163537000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ppe.12310"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,8]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.1111\/ppe.12310"],"URL":"https:\/\/doi.org\/10.1111\/ppe.12310","archive":["Portico"],"relation":{},"ISSN":["0269-5022","1365-3016"],"issn-type":[{"value":"0269-5022","type":"print"},{"value":"1365-3016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,8]]}}}