{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T02:03:00Z","timestamp":1791338580031,"version":"4.3.1"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,8,24]],"date-time":"2016-08-24T00:00:00Z","timestamp":1471996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Socio\u2010economic status is related to many life style and environmental factors, some of which have been suggested to influence the risk of childhood cancer. Studies requiring subject participation are usually hampered by selection of more educated parents. To prevent such bias, we used unselected nationwide Geographical Information System (<jats:styled-content style=\"fixed-case\">GIS<\/jats:styled-content>)\u2010based registry data, to investigate the influence of socio\u2010economic disparities on the risk of childhood cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The Geocap study included all French residents diagnosed with cancer aged up to 15 years over the period 2002\u20132010 (15 111 cases) and 45 000 contemporaneous controls representative of the childhood population. Area socio\u2010economic characteristics used to calculate the European Deprivation Index (<jats:styled-content style=\"fixed-case\">EDI<\/jats:styled-content>) were based on census data collected on the fine scale of the Merged Islet for Statistical Information (<jats:styled-content style=\"fixed-case\">IRIS<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, the risk of acute lymphoblastic leukaemia (<jats:styled-content style=\"fixed-case\">ALL<\/jats:styled-content>) was lower in the most deprived quintile than in the other quintiles of <jats:styled-content style=\"fixed-case\">EDI<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content><jats:sub>Q5vs&lt;Q5<\/jats:sub> 0.80 (95% confidence interval (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>) 0.73, 0.88)). The odds ratio for all the other cancers taken together was close to the null (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content><jats:sub>Q5vs&lt;Q5<\/jats:sub> 0.99 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.94, 1.04)).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Living in the most deprived areas was inversely associated with the risk of <jats:styled-content style=\"fixed-case\">ALL<\/jats:styled-content> in childhood. There was no indication that the risk of childhood cancer of any site could be increased by deprivation. Life style or environmental factors potentially underlying the association need further investigation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ppe.12313","type":"journal-article","created":{"date-parts":[[2016,8,24]],"date-time":"2016-08-24T08:06:39Z","timestamp":1472025999000},"page":"612-622","source":"Crossref","is-referenced-by-count":40,"title":["Risk of Childhood Cancer and Socio\u2010economic Disparities: Results of the French Nationwide Study Geocap 2002\u20132010"],"prefix":"10.1111","volume":"30","author":[{"given":"Fabienne","family":"Marquant","sequence":"first","affiliation":[{"name":"Epidemiology and Biostatistics Sorbonne Paris Cit\u00e9 Centre (CRESS) Epidemiology of childhood and adolescent cancers research group (EPICEA) INSERM UMR 1153 Paris Descartes University Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phanie","family":"Goujon","sequence":"additional","affiliation":[{"name":"Epidemiology and Biostatistics Sorbonne Paris Cit\u00e9 Centre (CRESS) Epidemiology of childhood and adolescent cancers research group (EPICEA) INSERM UMR 1153 Paris Descartes University Villejuif France"},{"name":"French National Registry of Childhood Haematological Malignancies (NRCH) Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laure","family":"Faure","sequence":"additional","affiliation":[{"name":"Epidemiology and Biostatistics Sorbonne Paris Cit\u00e9 Centre (CRESS) Epidemiology of childhood and adolescent cancers research group (EPICEA) INSERM UMR 1153 Paris Descartes University Villejuif France"},{"name":"French National Registry of Childhood Haematological Malignancies (NRCH) Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Guissou","sequence":"additional","affiliation":[{"name":"French National Registry of Childhood Solid Tumours (NRCST) Vandoeuvre\u2010les\u2010Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Orsi","sequence":"additional","affiliation":[{"name":"Epidemiology and Biostatistics Sorbonne Paris Cit\u00e9 Centre (CRESS) Epidemiology of childhood and adolescent cancers research group (EPICEA) INSERM UMR 1153 Paris Descartes University Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"H\u00e9mon","sequence":"additional","affiliation":[{"name":"Epidemiology and Biostatistics Sorbonne Paris Cit\u00e9 Centre (CRESS) Epidemiology of childhood and adolescent cancers research group (EPICEA) INSERM UMR 1153 Paris Descartes University Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Lacour","sequence":"additional","affiliation":[{"name":"French National Registry of Childhood Solid Tumours (NRCST) Vandoeuvre\u2010les\u2010Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Clavel","sequence":"additional","affiliation":[{"name":"Epidemiology and Biostatistics Sorbonne Paris Cit\u00e9 Centre (CRESS) Epidemiology of childhood and adolescent cancers research group (EPICEA) INSERM UMR 1153 Paris Descartes University Villejuif France"},{"name":"French National Registry of Childhood Haematological Malignancies (NRCH) Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1999.tb08101.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa0707519"},{"key":"e_1_2_6_4_1","unstructured":"La sant\u00e9 des enfants en grande section de maternelle en 2005\u20102006 [Internet]; 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