{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T13:23:24Z","timestamp":1789565004882,"version":"build-2803163510"},"reference-count":47,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,11,16]],"date-time":"2020-11-16T00:00:00Z","timestamp":1605484800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Both young and advanced maternal age have been associated with higher risks of neonatal mortality, but most studies are from high\u2010income countries and the evidence from low\u2010 and middle\u2010income countries (LMICs) is scarce.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the association between maternal age at delivery and neonatal mortality in LMICs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is a cross\u2010sectional study using data from 159 Demographic and Health Surveys in 67 LMICs between 2000 and 2018. Maternal age at the time of the birth was the exposure variable, and neonatal mortality was the outcome. Multivariable logistic regression model taking into consideration complex survey design was performed with adjustments for maternal education level, paternal education level, rural\/urban residence, country, and survey year. Subgroup analyses were performed by time of death, sex, the country's World Bank income classification, the World Health Organization region, and survey year.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 1\u00a0395\u00a0746 mother\u2010neonate pairs were included. Overall, compared with neonates born to mothers aged 25\u201029\u00a0years, those born to younger mothers aged 20\u201024, 16\u201019 and 12\u201015\u00a0years were at an increased risk of mortality (adjusted odds ratio [OR] 1.24, 95% confidence interval [CI] 1.17, 1.30; OR 1.81, 95% CI 1.71, 1.93; OR 2.29, 95% CI 1.96, 2.67, respectively). Neonates born to mothers aged 30\u201034, 35\u201039, 40\u201044, and \u226545\u00a0years were also at an increased risk of mortality (OR 1.09, 95% CI 1.03, 1.15; OR 1.30, 95% CI 1.21, 1.39; OR 1.50, 95% CI 1.38, 1.64; OR 1.84, 95% CI 1.54, 2.20, respectively). The results were consistent across most subgroup analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Neonates born to younger (&lt;25\u00a0years) and older mothers (\u226530\u00a0years) are at increased risk of neonatal death in LMICs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ppe.12734","type":"journal-article","created":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T00:06:29Z","timestamp":1605571589000},"page":"318-327","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Maternal age at birth and neonatal mortality: Associations from 67 low\u2010income and middle\u2010income countries"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1002-0569","authenticated-orcid":false,"given":"Han","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Epidemiology School of Public Health Cheeloo College of Medicine Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Food Hygiene School of Public Health Cheeloo College of Medicine Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajun","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangchao","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Cardiovascular Epidemiology &amp; Department of Epidemiology Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences &amp; Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0491-5585","authenticated-orcid":false,"given":"Bo","family":"Xi","sequence":"additional","affiliation":[{"name":"Department of Epidemiology School of Public Health Cheeloo College of Medicine Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,16]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31575-6"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60869-1"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)71048-5"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.midw.2012.04.001"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6543a1"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-13-S3-S2"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/1010539511428949"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2013.11.017"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0195731"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12659"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.2307\/4594897"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0021932000015819"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.76.12.1416"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2007.00849.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0000000000000818"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002307"},{"key":"e_1_2_8_18_1","first-page":"299","article-title":"Relationships between pregnancy spacing, sex of infants, maternal age, and birth order, and neonatal and post\u2010neonatal mortality in Bangladesh","volume":"28","author":"Swenson I","year":"1981","journal-title":"Soc Biol"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0186287"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dys184"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwx177"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(15)00038-8"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp048087"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e318225c2be"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyy209"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.7189\/jogh.08.010404"},{"key":"e_1_2_8_27_1","unstructured":"World Health Organization.Verbal Autopsy Standards: Ascertaining and Attributing Cause of Death.2007; 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