{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:31:52Z","timestamp":1791952312789,"version":"4.3.4"},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T00:00:00Z","timestamp":1641254400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Public health measures (PHM) designed to contain the spread of COVID\u201019 pandemic have influenced the epidemiological characteristics of other viral infections. Its impact on acute RSV bronchiolitis in infants of \u226424\u00a0months old has not been systematically studied in our setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To describe the monthly pattern of visits to the Paediatric Emergency Department (PED) of patients 0 to 14\u00a0years of age, the rate of patients diagnosed with RSV acute bronchiolitis per thousand inhabitants of 0 to 24\u00a0months, and the rate of them requiring hospital admission during the winter 2020\u20132021, in the context of local and national COVID\u201019 restrictions and compare them to the four previous seasons.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Interrupted time series analysis of patients assisted in the PED and diagnosed with or admitted for RSV acute bronchiolitis in a tertiary University Hospital from January 2016 to February 2020 (pre\u2010intervention period) and from March 2020 to June 2021 (post\u2010intervention period). Intervention: Preventive PHM implemented by the Spanish government weighted by the Containment and Health Index of the Oxford COVID\u201019 Government Response Tracker.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The intervention was followed by an immediate reduction of the rate of visits to the PED of \u201319.5 (95% confidence interval [CI] \u201324.0, \u201314.9) per thousand, and the rate of diagnoses and admissions for RSV acute bronchiolitis of \u201344.3 (95% CI \u201373.8, \u201314.8) and \u20131.4 (95% CI \u20132.7, \u20130.1) per thousand, respectively, with a delayed rebound.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>After the implementation of PHM to prevent the spread of SARS\u2010CoV\u20102 infection, an immediate and important decline in the visits to the PED was observed, with an upward change thereafter. There was also an initial reduction in the diagnoses of and admissions by RSV acute bronchiolitis. An upward trend was observed six to nine months after the usual time of the winter RSV epidemic, coinciding with the relaxation of the preventive PHM.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ppe.12829","type":"journal-article","created":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T07:49:20Z","timestamp":1641282560000},"page":"329-336","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Effects of public health measures during the SARS\u2010CoV\u20102 pandemic on the winter respiratory syncytial virus epidemic: An interrupted time series analysis"],"prefix":"10.1111","volume":"36","author":[{"given":"Ana Isabel","family":"Reyes Dom\u00ednguez","sequence":"first","affiliation":[{"name":"Department of Paediatrics Hospital Universitario Materno\u2010Infantil de Las Palmas  Las Palmas de Gran Canaria Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svetlana","family":"Pavlovic Nesic","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Hospital Universitario Materno\u2010Infantil de Las Palmas  Las Palmas de Gran Canaria Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lourdes","family":"Urqu\u00eda Mart\u00ed","sequence":"additional","affiliation":[{"name":"Division of Neonatology Hospital Universitario Materno\u2010Infantil de Las Palmas  Las Palmas de Gran Canaria Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda del Carmen","family":"P\u00e9rez Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Microbiology Hospital Universitario Dr. Negr\u00edn  Las Palmas de Gran Canaria Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Desiderio","family":"Reyes Su\u00e1rez","sequence":"additional","affiliation":[{"name":"Division of Neonatology Hospital Universitario Materno\u2010Infantil de Las Palmas  Las Palmas de Gran Canaria Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6028-9158","authenticated-orcid":false,"given":"Ferm\u00edn","family":"Garc\u00eda\u2010Mu\u00f1oz Rodrigo","sequence":"additional","affiliation":[{"name":"Division of Neonatology Hospital Universitario Materno\u2010Infantil de Las Palmas  Las Palmas de Gran Canaria Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,1,4]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31829b7e43"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23570"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acap.2014.06.008"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2020.25.47.2001847"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2702.204041"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-2667(20)30090-6"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000002845"},{"issue":"6","key":"e_1_2_11_9_1","first-page":"12","article-title":"Minimum sample size requirements for seasonal forecasting models","volume":"6","author":"Hyndman R","year":"2007","journal-title":"Foresight Int J Appl Forecast"},{"key":"e_1_2_11_10_1","unstructured":"HaleT AnaniaJ&AngristNet al.Variation in Government Responses to COVID\u201019. 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Accessed July 14 2021."},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-2223"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12874-021-01235-8"},{"key":"e_1_2_11_13_1","volume-title":"R: A language and environment for statistical computing","author":"R Core Team","year":"2020"},{"issue":"10","key":"e_1_2_11_14_1","doi-asserted-by":"crossref","first-page":"e649","DOI":"10.1093\/cid\/ciaa1256","article-title":"Concomitant marked decline in prevalence of severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102) and other respiratory viruses among symptomatic patients following public health interventions in Australia: data from St Vincent's hospital and associated screening clinics, Sydney, NSW","volume":"72","author":"Marriott D","year":"2021","journal-title":"Clin Infect Dis"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-5247(20)30114-2"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1911083116"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2013182117"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1101\/2021.03.12.21253446"}],"container-title":["Paediatric and Perinatal Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ppe.12829","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ppe.12829","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ppe.12829","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T08:03:21Z","timestamp":1692950601000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ppe.12829"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,4]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1111\/ppe.12829"],"URL":"https:\/\/doi.org\/10.1111\/ppe.12829","archive":["Portico"],"relation":{},"ISSN":["0269-5022","1365-3016"],"issn-type":[{"value":"0269-5022","type":"print"},{"value":"1365-3016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,4]]},"assertion":[{"value":"2021-05-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}