{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:46:59Z","timestamp":1792086419006,"version":"4.4.0"},"reference-count":59,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,4,18]],"date-time":"2022-04-18T00:00:00Z","timestamp":1650240000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007560","name":"Chiesi Farmaceutici","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007560","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Developmental coordination disorder (DCD) is a motor disorder of unknown aetiology that may have long\u2010term consequences on daily activities, and psychological and physical health. Studies investigating risk factors for DCD have so far provided inconsistent results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess, using a parent\u2010report screening tool, risk of DCD in school\u2010age very preterm children born in Italy, and investigate the associated early biomedical and sociodemographic factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective area\u2010based cohort (804 children, response rate 73.4%) was assessed at 8\u201311\u00a0years of age in three Italian regions. Perinatal data were abstracted from medical records. DCD risk was measured using the Italian\u2010validated version of the Developmental Coordination Disorder Questionnaire (DCDQ\u2010IT). For this study, children with cognitive deficit (i.e. intelligence quotient &lt;70), cerebral palsy, severe vision and hearing disabilities, and other impairments affecting movement were excluded. A total of 629 children were analysed. We used inverse probability weighting to account for loss to follow\u2010up, and multilevel, multivariable modified Poisson models to obtain adjusted risk ratio (aRR) and 95% confidence interval (CI). Missing values in the covariates were imputed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>195 children (weighted proportion 31.8%, 95% CI 28.2, 35.6) scored positive on the DCDQ\u2010IT, corresponding to the 15th centile of the reference Movement\u2010ABC test. Factors associated with overall DCD risk were male sex (aRR 1.35, 95% CI 1.05, 1.73), intrauterine growth restriction (aRR 1.45, 95% CI 1.14, 1.85), retinopathy of prematurity (aRR 1.62, 95% CI 1.07, 2.45), and older maternal age at delivery (aRR 1.39, 95% CI 1.09, 1.77). Complete maternal milk feeding at discharge from the neonatal unit and higher parental socio\u2010economic status were associated with decreased risk.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Both biomedical and sociodemographic factors increase DCD risk. These findings can contribute to elucidating the origins of this disorder, and assist in the identification of children at risk for early referral and intervention.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ppe.12878","type":"journal-article","created":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T04:47:03Z","timestamp":1650343623000},"page":"683-695","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Early factors associated with risk of developmental coordination disorder in very preterm children: A prospective area\u2010based cohort study in Italy"],"prefix":"10.1111","volume":"36","author":[{"given":"Stefania","family":"Zoia","sequence":"first","affiliation":[{"name":"Struttura Complessa Tutela Salute Bambini Adolescenti Donne Famiglia Azienda Sanitaria Universitaria Giuliano Isontina  Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Biancotto","sequence":"additional","affiliation":[{"name":"Struttura Complessa Tutela Salute Bambini Adolescenti Donne Famiglia Azienda Sanitaria Universitaria Giuliano Isontina  Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Caravale","sequence":"additional","affiliation":[{"name":"Department of Developmental and Social Psychology La Sapienza University  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Valletti","sequence":"additional","affiliation":[{"name":"Clinical Care and Management Innovation Research Area Bambino Ges\u00f9 Children\u2019s Hospital IRCCS  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Montelisciani","sequence":"additional","affiliation":[{"name":"Clinical Care and Management Innovation Research Area Bambino Ges\u00f9 Children\u2019s Hospital IRCCS  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ileana","family":"Croci","sequence":"additional","affiliation":[{"name":"Clinical Care and Management Innovation Research Area Bambino Ges\u00f9 Children\u2019s Hospital IRCCS  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Voller","sequence":"additional","affiliation":[{"name":"Unit of Epidemiology Regional Health Agency of Tuscany  Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franca","family":"Rusconi","sequence":"additional","affiliation":[{"name":"Unit of Epidemiology Meyer Children's University Hospital  Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Carrozzi","sequence":"additional","affiliation":[{"name":"Department of Neuroscience Burlo Garofolo Maternal and Child Health Hospital IRCCS  Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"Chiandotto","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, S. Maria della Misericordia University Hospital  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Di Lallo","sequence":"additional","affiliation":[{"name":"Hospital Network Planning and Research Area Lazio Regional Health Authority  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Vicari","sequence":"additional","affiliation":[{"name":"Department of Life Sciences and Public Health Catholic University, and Department of Neuroscience Child &amp; Adolescent Psychiatry Unit Bambino Ges\u00f9 Children\u2019s Hospital IRCCS  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3284-6874","authenticated-orcid":false,"given":"Marina","family":"Cuttini","sequence":"additional","affiliation":[{"name":"Clinical Care and Management Innovation Research Area Bambino Ges\u00f9 Children\u2019s Hospital IRCCS  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,18]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.14132"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2012-302268"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12223"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpn.2019.01.002"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2020.103699"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2020.101116"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2020.12.022"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2017.10.014"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2018.05.011"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-1556"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12137"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2018.05.012"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2018.1394"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2012.06.005"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.14781"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-3782(99)00017-1"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2016.02.007"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/ped.14275"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2015.03.006"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2019.00438"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2014.01.001"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2007.134692"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12743"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.161.11.1053"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.13435"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.14786"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2014.04.023"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.15152"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1413-35552013005000096"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.paed.2009.08.027"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.13899"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1080\/01942630902784761"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpn.2013.11.009"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2014.10.035"},{"key":"e_1_2_9_37_1","volume-title":"Four\u2010factor index of social status","author":"Hollingshead AA","year":"1975"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1177\/0962280211427759"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12874-021-01264-3"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4067"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.140994"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3016.2001.00321.x"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1080\/14622200701491255"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa041367"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742-2094-11-100"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2013.10.012"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwm327"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2015.06.004"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2016-312533"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1159\/000487847"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.112.5.1016"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2019.05.012"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ghir.2017.11.006"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2013.52"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-018-5650-z"},{"key":"e_1_2_9_56_1","article-title":"Early detection of cognitive, language, and motor delays for low\u2010income preterm infants: a Brazilian cohort longitudinal study on infant neurodevelopment and maternal practice","volume":"12","author":"Valentini NC","year":"2021","journal-title":"Front Psych"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2009.03.012"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2016.06.045"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.116.144279"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2021.118084"}],"container-title":["Paediatric and Perinatal Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ppe.12878","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ppe.12878","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ppe.12878","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T07:48:48Z","timestamp":1692776928000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ppe.12878"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,18]]},"references-count":59,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1111\/ppe.12878"],"URL":"https:\/\/doi.org\/10.1111\/ppe.12878","archive":["Portico"],"relation":{},"ISSN":["0269-5022","1365-3016"],"issn-type":[{"value":"0269-5022","type":"print"},{"value":"1365-3016","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,18]]},"assertion":[{"value":"2021-10-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}