{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T02:06:33Z","timestamp":1789178793170,"version":"build-2803163510"},"reference-count":44,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T00:00:00Z","timestamp":1708128000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01\u2010HL150065"],"award-info":[{"award-number":["R01\u2010HL150065"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["R01\u2010ES033190"],"award-info":[{"award-number":["R01\u2010ES033190"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Pre\u2010existing health conditions increase the risk of obstetric complications during pregnancy and birth. However, the prevalence and recent changes in the frequency of pre\u2010existing health conditions in the childbearing population remain unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To estimate the temporal changes in the prevalence of pre\u2010existing health conditions among pregnant women in British Columbia, Canada.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We carried out a population\u2010based cross\u2010sectional study of 825,203 deliveries in BC between 2000 and 2019 and examined 17 categories of physical and psychiatric health conditions recorded within 5\u2009years before childbirth. We also undertook age\u2010period\u2010cohort analyses to evaluate temporal changes in pre\u2010existing health conditions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of any pre\u2010existing health condition was 26.2% (<jats:italic>n<\/jats:italic>\u2009=\u2009216,214) with overall trends remaining stable during the study period. Between 2000 and 2019, the prevalence rates of anxiety (5.6%\u20139.6%), bipolar (1.6%\u20133.4%), psychosis (0.7%\u20130.8%), and eating disorders (0.2%\u20130.3%) increased. The prevalence of hypertension increased sharply from 0.06% in 2000 to 0.3% in 2019. Diabetes mellitus and stroke rates increased, as did the prevalence of systemic lupus, multiple sclerosis, and chronic kidney disease. Advanced maternal age was strongly associated with both psychiatric and circulatory\/metabolic conditions. A strong birth cohort effect was evident, with rates of psychiatric conditions increasing among women born after 1985.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In British Columbia, Canada, 1 in 4 mothers had a pre\u2010existing health condition 5\u2009years prior to pregnancy. These findings underscore the need for multi\u2010disciplinary care for women with pre\u2010existing health conditions to improve maternal, foetal, and infant health.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ppe.13060","type":"journal-article","created":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T08:31:02Z","timestamp":1708158662000},"page":"383-393","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Temporal changes in <scp>pre\u2010existing<\/scp> health conditions five years prior to pregnancy in British Columbia, Canada, 2000\u20132019"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2407-2151","authenticated-orcid":false,"given":"Louise","family":"Lundborg","sequence":"first","affiliation":[{"name":"Clinical Epidemiology Division, Department of Medicine Solna Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. S.","family":"Joseph","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Children's and Women's Hospital of British Columbia University of British Columbia  Vancouver British Columbia Canada"},{"name":"School of Population and Public Health University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1220-310X","authenticated-orcid":false,"given":"Sarka","family":"Lisonkova","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Children's and Women's Hospital of British Columbia University of British Columbia  Vancouver British Columbia Canada"},{"name":"School of Population and Public Health University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wee\u2010Shian","family":"Chan","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine, Department of Medicine, Children's and Women's Hospital of British Columbia University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Wen","sequence":"additional","affiliation":[{"name":"School of Population and Public Health University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0410-2595","authenticated-orcid":false,"given":"Cande V.","family":"Ananth","sequence":"additional","affiliation":[{"name":"Division of Epidemiology and Biostatistics, Department of Obstetrics, Gynecology, and Reproductive Sciences Rutgers Robert Wood Johnson Medical School  New Brunswick New Jersey USA"},{"name":"Cardiovascular Institute of New Jersey Rutgers Robert Wood Johnson Medical School  New Brunswick New Jersey USA"},{"name":"Department of Medicine Rutgers Robert Wood Johnson Medical School  New Brunswick New Jersey USA"},{"name":"Department of Biostatistics and Epidemiology Rutgers School of Public Health  Piscataway New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neda","family":"Razaz","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Division, Department of Medicine Solna Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,17]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2393-14-75"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002357"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002864"},{"key":"e_1_2_11_5_1","unstructured":"MathewsTJ HamiltonBE.First births to older women continue to rise;2014."},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60460-8"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12958-016-0225-2"},{"key":"e_1_2_11_8_1","first-page":"13","article-title":"Provincial variations in birth outcomes according to maternal country of birth, 2000\u20132016","volume":"31","author":"Lee JB","year":"2020","journal-title":"Health Rep"},{"key":"e_1_2_11_9_1","volume-title":"Live Births by Age of Mother. 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