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We hypothesize that local PM sources are related to poorer children's respiratory health.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>Elementary school children in Imperial Valley, CA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Prospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between 2017 and 2019, we collected baseline information on 731 children, then follow\u2010up assessments yearly or twice\u2010yearly since 2019. Data have been collected on children's respiratory health, demographics, household characteristics, physical activity and lifestyle, via questionnaires completed by parents or primary caregivers. In\u2010person measurements, conducted since 2019, repeatedly assessed lung function, height, weight and blood pressure. Exposure to air pollutants has been assessed by multiple methods and individually assigned to participants using residential and school addresses. Health data will be linked to ambient and local sources of PM, during and preceding the study period to understand how spatiotemporal trends in these environmental exposures may relate to respiratory health.<\/jats:p><\/jats:sec><jats:sec><jats:title>Preliminary Results<\/jats:title><jats:p>Analyses of respiratory symptoms indicate a high prevalence of allergies, bronchitic symptoms and wheezing. Asthma diagnosis was reported in 24% of children at enrolment, which exceeds both CA state and US national prevalence estimates for children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The Children's AIRE cohort, while focused on the health impacts of the drying Salton Sea and air quality in Imperial Valley, is poised to elucidate the growing threat of drying saline lakes and wind\u2010blown dust sources to respiratory health worldwide, as sources of wind\u2010blown dust emerge in our changing climate.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ppe.13065","type":"journal-article","created":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T11:15:49Z","timestamp":1709810149000},"page":"359-369","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Cohort profile: The Assessing Imperial Valley Respiratory Health and the Environment (<scp>AIRE<\/scp>) study"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9897-3692","authenticated-orcid":false,"given":"Shohreh F.","family":"Farzan","sequence":"first","affiliation":[{"name":"Department of Population and Public Health Sciences, Keck School of Medicine University of Southern California  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3543-1623","authenticated-orcid":false,"given":"Elizabeth","family":"Kamai","sequence":"additional","affiliation":[{"name":"Department of Population and Public Health Sciences, Keck School of Medicine University of Southern California  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dayane","family":"Duenas\u00a0Barahona","sequence":"additional","affiliation":[{"name":"Department of Population and Public Health Sciences, Keck School of Medicine University of Southern California  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshira Van Horne","family":"Ornelas","sequence":"additional","affiliation":[{"name":"Department of Environmental Health Sciences, Mailman School of Public Health Columbia University  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2233-2706","authenticated-orcid":false,"given":"Christopher","family":"Zuidema","sequence":"additional","affiliation":[{"name":"Department of Environmental and Occupational Health Sciences University of Washington  Seattle Washington USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Wong","sequence":"additional","affiliation":[{"name":"Tracking California, Public Health Institute  Oakland California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Torres","sequence":"additional","affiliation":[{"name":"Comite Civico del Valle  Brawley California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther","family":"Bejarano","sequence":"additional","affiliation":[{"name":"Comite Civico del Valle  Brawley California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edmund","family":"Seto","sequence":"additional","affiliation":[{"name":"Department of Environmental and Occupational Health Sciences University of Washington  Seattle Washington USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"English","sequence":"additional","affiliation":[{"name":"Tracking California, Public Health Institute  Oakland California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Olmedo","sequence":"additional","affiliation":[{"name":"Comite Civico del Valle  Brawley California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jill","family":"Johnston","sequence":"additional","affiliation":[{"name":"Department of Population and Public Health Sciences, Keck School of Medicine University of Southern California  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,3,7]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(13)70118-8"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/10889388.1998.10641085"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/1753465813479428"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-2354"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2014.302172"},{"key":"e_1_2_12_7_1","unstructured":"Bureau U.S.C. 2010 Census.2014."},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2019.01.365"},{"key":"e_1_2_12_9_1","unstructured":"Breathing C.D.o.P.H.C.California Asthma Dashboard. 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